Gene 2 Function Project

The gene2function (g2f) project aims to determine the functions of such putative enzymes in the methanogenic Archaea, Methanosarcina acetivorans. This organism has the largest genome of any Archaea (5.8 Mb) with 4524 predicted coding sequences, and is one of the most metabolically diverse Archaea. Approximately half of these genes fall into the putative enzyme category and include genes possibly involved in processes such as methanogenesis, nitrogen fixation, and carbon assimilation. Given the importance of methanogens in global carbon flow and as a potential source of energy, a complete understanding of gene function in these organisms is essential.