NIST BMD Seminar: “Structure-Function Studies of the SARS-CoV-2 Spike and Development of COVID-19 Interventions”

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Event Type: 
Contact Person: 
Mike Tarlov
Event Info
Sep 7 2021 - 11:00am to 12:00pm
Jason McLellan
Speaker Affiliation: 
University of Texas at Austin
Event Description: 

During this presentation I will discuss my laboratory’s collaborative work understanding the structure and function of coronavirus spike proteins, and how we leveraged this information to design novel vaccine antigens that are in four leading COVID-19 vaccines. I will also describe how we were able to rapidly determine the structure of the SARS-CoV-2 spike protein in early 2020 and leverage that information into the design of second-generation spikes that are more stable and express better than our initial antigen. I will also discuss our recent work on spike-directed antibodies. 


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Meeting ID: 969 9269 0266
Passcode: 898440

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Meeting ID: 969 9269 0266