New Tools for Neurobiology via mRNA Display

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Event Type: 
Contact Person: 
Event Info
Date: 
Wednesday, October 17, 2018 - 11:00am to 1:00pm
Location: 
Auditorium
2112
Details
Speaker/Presenter: 
Richard Roberts
Speaker Title: 
Professor
Speaker Affiliation: 
USC
Event Description: 

A central goal of neurobiology is understanding the structure, function, and dynamics of proteins within living neurons.  Our laboratory has addressed this issue by working to develop genetically encoded probes that can be used to explore, modulate, and ablate the function of the proteins they target.  To do this, we use directed evolution via mRNA display to engineer disulfide-free, high-affinity reagents targeted to specific neuronal proteins.  The talk will describe our recent efforts targeting neuronal proteins and the directed evolution methods we use to create these tools. 

Setup
IT Setup: 
Projector
Laptop
Streaming on YouTube
Podium
Lavalier Microphone
Wireless PPT Remote