Highly efficient C-to-T and A-to-G base editing in a Populus hybrid.

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TitleHighly efficient C-to-T and A-to-G base editing in a Populus hybrid.
Publication TypeJournal Article
Year of Publication2021
AuthorsLi, G, Sretenovic, S, Eisenstein, E, Coleman, G, Qi, Y
JournalPlant Biotechnol J
Date Published2021 Mar 20
ISSN1467-7652
Abstract

CRISPR-Cas based genome editing technologies hold great potential for genetic research and bioengineering in trees. CRISPR-Cas9 was previously demonstrated to be a highly efficient genome editing system in poplar (Zhou et al., 2015). However, these applications only used the nuclease activity of Cas9 for targeted mutagenesis. By contrast, Cas9-derived base editors can install specific base changes in a plant genome.

DOI10.1111/pbi.13581
Alternate JournalPlant Biotechnol J
PubMed ID33742755