Structure of yeast phenylalanine transfer RNA at 2.5 A resolution.

Printer-friendly versionPrinter-friendly versionPDF versionPDF version
TitleStructure of yeast phenylalanine transfer RNA at 2.5 A resolution.
Publication TypeJournal Article
Year of Publication1975
AuthorsLadner, JE, Jack, A, Robertus, JD, Brown, RS, Rhodes, D, Clark, BF, Klug, A
JournalProc Natl Acad Sci U S A
Date Published1975 Nov
KeywordsBase Sequence, Hydrogen Bonding, Models, Structural, Nucleic Acid Conformation, Phenylalanine, RNA, Transfer, Saccharomyces cerevisiae, X-Ray Diffraction

The x-ray analysis of the monoclinic form of yeast tRNAPhe has been taken to a resolution of 2.5 A by the method of isomorphous replacement. The model proposed at 3 A has been confirmed and extended to reveal additional features of the tertiary structure and of the stereochemistry. An extensive hydrogen bonding network is described involving specific interactions between bases and the ribose-phosphate backbone. The structure of a G-U base pair has been solved.

Alternate JournalProc. Natl. Acad. Sci. U.S.A.
PubMed ID1105583
PubMed Central IDPMC388732