Structure of yeast phenylalanine transfer RNA at 2.5 A resolution.

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TitleStructure of yeast phenylalanine transfer RNA at 2.5 A resolution.
Publication TypeJournal Article
Year of Publication1975
AuthorsLadner, JE, Jack, A, Robertus, JD, Brown, RS, Rhodes, D, Clark, BF, Klug, A
JournalProc Natl Acad Sci U S A
Volume72
Issue11
Pagination4414-8
Date Published1975 Nov
ISSN0027-8424
KeywordsBase Sequence, Hydrogen Bonding, Models, Structural, Nucleic Acid Conformation, Phenylalanine, RNA, Transfer, Saccharomyces cerevisiae, X-Ray Diffraction
Abstract

The x-ray analysis of the monoclinic form of yeast tRNAPhe has been taken to a resolution of 2.5 A by the method of isomorphous replacement. The model proposed at 3 A has been confirmed and extended to reveal additional features of the tertiary structure and of the stereochemistry. An extensive hydrogen bonding network is described involving specific interactions between bases and the ribose-phosphate backbone. The structure of a G-U base pair has been solved.

Alternate JournalProc. Natl. Acad. Sci. U.S.A.
PubMed ID1105583
PubMed Central IDPMC388732