Conservation of the molecular structure of yeast phenylalanine transfer RNA in two crystal forms.

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TitleConservation of the molecular structure of yeast phenylalanine transfer RNA in two crystal forms.
Publication TypeJournal Article
Year of Publication1974
AuthorsKlug, A, Robertus, JD, Ladner, JE, Brown, RS, Finch, JT
JournalProc Natl Acad Sci U S A
Volume71
Issue9
Pagination3711-5
Date Published1974 Sep
ISSN0027-8424
KeywordsModels, Molecular, Models, Structural, Phenylalanine, RNA, Transfer, X-Ray Diffraction, Yeasts
Abstract

A comparison is made between the electron density maps of the monoclinic and orthorhombic crystal forms of yeast tRNA(Phe) which have been obtained respectively by ourselves and by another group. It is concluded that the molecular structures are essentially the same in both crystals, although the models derived from the maps are not the same. The relation between the two molecular packings is discussed, and it is suggested that the intermolecular contact in the orthorhombic form which is not present in the monoclinic form, may arise through base pairing of the anticodons of neighboring molecules.

Alternate JournalProc. Natl. Acad. Sci. U.S.A.
PubMed ID4530331
PubMed Central IDPMC433846