Unwinding twenty years of the archaeal minichromosome maintenance helicase.

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TitleUnwinding twenty years of the archaeal minichromosome maintenance helicase.
Publication TypeJournal Article
Year of Publication2020
AuthorsKelman, LM, O'Dell, WB, Kelman, Z
JournalJ Bacteriol
Date Published2020 Jan 06
ISSN1098-5530
Abstract

Replicative DNA helicases are essential cellular enzymes that unwind duplex DNA in front of the replication fork during chromosomal DNA replication. Replicative helicases were discovered, beginning in the 1970s, in bacteria, bacteriophages, viruses, eukarya, and, in the mid-1990s, in archaea. This year marks the 20 anniversary of the first report on the archaeal replicative helicase, the minichromosome maintenance (MCM) protein. This minireview summarizes two decades of work on the archaeal MCM.

DOI10.1128/JB.00729-19
Alternate JournalJ. Bacteriol.
PubMed ID31907204