IBBR Fellows

IBBR Scientists. Experts exploring new horizons. And advancing understanding.

IBBR unites distinguished scientists from the University of Maryland, College Park and the University of Maryland, Baltimore, and from the National Institute of Standards and Technology (NIST). Our Fellows come together across disciplines and institutions to discover tomorrow's biotechnology solutions.

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Name Profile
John Schiel
Biomolecular Measurement Division

Biomanufacturing and characterization of the ever-increasing cadre of complex therapeutics (protein therapeutics, biologics, cell, and gene therapies) are approaching the point at which disruptive technology may be necessary to advance next generation drugs. With each molecular class come new challenges in the elucidation of structure, mechanism of action, stability, and immunogenicity, as well as regulatory considerations that must be addressed to ensure safety and efficacy. Dr. Schiel develops innovative approaches to the production, characterization, and de-risking of innovative next generation biotherapeutics. His research utilizes a wide variety of instrumentation including high-resolution mass spectrometry, one- and two-dimensional, ultrahigh performance liquid chromatography, capillary electrophoresis, and surface plasmon resonance.

Vitalii Silin
Institute for Bioscience and Biotechnology Research

Dr. Vitalii Silin is a physicist with a wide interdisciplinary background that includes spectroscopy, optics, electrochemistry, neutron reflectometry (NR), electron microscopy (EM), biophysics and biochemistry. He studies the structure and function of integral membrane proteins (IMPs) and peptides imbedded into phospholipid bilayers. Dr. Silin’s laboratory uses a platform developed at NIST and IBBR based on tethered bilayer phospholipid membranes (tBLMs) and synchronized surface plasmon resonance/electrochemical impedance spectroscopy (SPR/EIS) measurements, as well as NR and cryogenic EM, to study membrane active biomolecules.

Arlin Stoltzfus
Biosystems & Biomaterials Division

Dr. Stoltzfus's research addresses issues in molecular evolution, bioinformatics, and evolutionary theory that are amenable to computer-based approaches. The group explores models and tests hypotheses, develops software, and participates in community efforts to improve interoperability. A major ongoing interest is understanding the role of mutation in evolution, an area where the group has developed novel theory and presented novel results on the foundational issue of how biases in mutation influence the course of evolution. Other topics of interest include the evolution of introns, Bayesian methods for fossil calibration of phylogenies, models of constructive neutral evolution, and the history and philosophy of evolutionary biology.