Infectious diseases continue to pose significant risks to human, animal and plant health. A better understanding of these threats – and the mechanisms that host cells mount to fend off the infections – is key to the diagnosing, treating and preventing the spread of disease.
IBBR uses reverse and forward genetic approaches and DNA transformation technologies with model and pathogenic organisms to understand and manipulate gene regulation and function in the context of disease. This research will lead to a better understanding of the biological, biochemical and biophysical processes of host-pathogen interactions.
IBBR core researchers associated with Host Pathogen Interactions utilize major infrastructure that includes:
- Insect Transformation Facility
- Mass spectrometry
- Confocal microscopy
- Illumina sequencing core