Abstract: Nucleic acid vaccines are emerging alternatives for the prevention and treatment of infectious diseases as well as for pathologies such as cancer, allergies, autoimmune diseases, and drug dependencies. These vaccines induce the expression of encoded antigenic/therapeutic proteins or peptides (e.g., derived from a pathogen, a human self-protein, or a malignant neoplasm) in the body of an immunized (vaccinated) subject, and elicit adaptive immune responses, including humoral and cellular immune responses, as well as activate innate immune responses.
IBBR Seminar Series
Lignocellulosic biomass has the potential to play a major role in generation of renewable biofuels if cost-effective conversion can be achieved. Largely composed of plant cell walls, it is a complex biological composite material that is recalcitrant to the structural deconstruction and enzymatic hydrolysis into sugars that is necessary for fermentation to biofuels. Knowledge of how the plant cell wall is assembled and the changes that occur during pretreatment are critical to drive improvements in the conversion of renewable lignocellulosic biomass to biofuels.