IBBR Seminar Series

FcRn: From Biology to Therapeutics and Vaccine Development

This seminar will present current research on the in-depth analysis of the neonatal Fc receptor (FcRn) biology and implications of this knowledge on the development of therapeutics and vaccines. In early life, the neonatal Fc receptor (FcRn) establishes passive immunity by transporting maternal IgG antibody from mother to offspring. During adulthood, FcRn seeds mucosal immunity by mediating the transport of IgG across polarized epithelial cells lining the body’s mucosal surfaces.