IBBR Seminar Series

Molecular Organization of the Postsynaptic Density

In the brain, neuronal processes make numerous connections at specialized structures called synapses for neuronal communication, information processing and storage. This talk focuses on imaging synapses by electron microscopy with particular emphasis on recent development using EM tomography on high pressure frozen and freeze substituted hippocampal synapses to decipher the molecular level organization of the postsynaptic density (PSD).