Publications

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Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy.
Becette OB, Marino JP, Brinson RG. 2022. Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy. Pharmaceutical research : . DOI: 10.1007/s11095-022-03403-x
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.
Li Q, Humphries F, Girardin RC, Wallace A, Ejemel M, Amcheslavsky A, McMahon CT, Schiller ZA, Ma Z, Cruz J, et al. 2022. Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants. Frontiers in immunology 13: 995412. DOI: 10.3389/fimmu.2022.995412
Antibody interfaces revealed through structural mining.
Yin Y, Romei MG, Sankar K, Pal LR, Hoi KH, Yang Y, Leonard B, De Leon Boenig G, Kumar N, Matsumoto M, et al. 2022. Antibody interfaces revealed through structural mining. Computational and structural biotechnology journal 20: 4952-4968. DOI: 10.1016/j.csbj.2022.08.048
Scaffold hopping from indoles to indazoles yields dual MCL-1/BCL-2 inhibitors from MCL-1 selective leads.
Drennen B, Goodis CC, Bowen N, Yu W, Vickers G, Wilder PT, MacKerell AD, Fletcher S. 2022. Scaffold hopping from indoles to indazoles yields dual MCL-1/BCL-2 inhibitors from MCL-1 selective leads. RSC medicinal chemistry 13(8): 963-969. DOI: 10.1039/d2md00095d
Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models.
Thomas E, Thankan RS, Purushottamachar P, Huang W, Kane MA, Zhang Y, Ambulos NP, Weber DJ, Njar VCO. 2022. Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models. Cells 11(17): . DOI: 10.3390/cells11172699
Biopharmaceutical Manufacturing Readiness Levels (BRL) - A Shared Vocabulary for Biopharmaceutical Technology Development and Commercialization.
Kedia SB, Baker JC, Carbonell RG, Lee KH, Roberts CJ, Erickson J, Schiel JE, Rogers K, Schaefer G, Pluschkell S. 2022. Biopharmaceutical Manufacturing Readiness Levels (BRL) - A Shared Vocabulary for Biopharmaceutical Technology Development and Commercialization. Biotechnology and bioengineering : . DOI: 10.1002/bit.28227
Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study.
Mouchahoir T, Schiel JE, Rogers R, Heckert A, Place BJ, Ammerman A, Li X, Robinson T, Schmidt B, Chumsae CM, et al. 2022. Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study. Journal of the American Society for Mass Spectrometry : . DOI: 10.1021/jasms.2c00129
Acclimation and Compensating Metabolite Responses to UV-B Radiation in Natural and Transgenic Populus spp. Defective in Lignin Biosynthesis.
Wong TM, Sullivan JH, Eisenstein E. 2022. Acclimation and Compensating Metabolite Responses to UV-B Radiation in Natural and Transgenic <i>Populus</i> spp. Defective in Lignin Biosynthesis. Metabolites 12(8): . DOI: 10.3390/metabo12080767
Extension of the CHARMM Classical Drude Polarizable Force Field to N- and O-Linked Glycopeptides and Glycoproteins.
Kognole AA, Aytenfisu AH, MacKerell AD. 2022. Extension of the CHARMM Classical Drude Polarizable Force Field to N- and O-Linked Glycopeptides and Glycoproteins. The journal of physical chemistry. B : . DOI: 10.1021/acs.jpcb.2c04245
Time-resolved solid state NMR of biomolecular processes with millisecond time resolution.
Jeon J, Blake Wilson C, Yau WM, Thurber KR, Tycko R. 2022. Time-resolved solid state NMR of biomolecular processes with millisecond time resolution. Journal of magnetic resonance (San Diego, Calif. : 1997) 342: 107285. DOI: 10.1016/j.jmr.2022.107285
Nitroxide-based triradical dopants for efficient low-temperature dynamic nuclear polarization in aqueous solutions over a broad pH range.
Yau WM, Blake Wilson C, Jeon J, Tycko R. 2022. Nitroxide-based triradical dopants for efficient low-temperature dynamic nuclear polarization in aqueous solutions over a broad pH range. Journal of magnetic resonance (San Diego, Calif. : 1997) 342: 107284. DOI: 10.1016/j.jmr.2022.107284
Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development.
Lin M, Marin A, Ellis B, Eubanks LM, Andrianov AK, Janda KD. 2022. Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development. Molecular pharmaceutics : . DOI: 10.1021/acs.molpharmaceut.2c00489
Protein G: β-galactosidase fusion protein for multi-modal bioanalytical applications.
Motabar D, Wang S, Tsao CY, Payne GF, Bentley WE. 2022. Protein G: β-galactosidase fusion protein for multi-modal bioanalytical applications. Biotechnology progress : e3297. DOI: 10.1002/btpr.3297
Quorum sensing componentry opens new lines of communication.
Wang S, Payne GF, Bentley WE. 2022. Quorum sensing componentry opens new lines of communication. The EMBO journal : e112162. DOI: 10.15252/embj.2022112162
Multicolor plate reader fluorescence calibration.
Beal J, Telmer CA, Vignoni A, Boada Y, Baldwin GS, Hallett L, Lee T, Selvarajah V, Billerbeck S, Brown B, et al. 2022. Multicolor plate reader fluorescence calibration. Synthetic biology (Oxford, England) 7(1): ysac010. DOI: 10.1093/synbio/ysac010