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Xiao Lab Awarded $2M NIH MIRA Award for Groundbreaking Plant Biology Research
The Institute for Bioscience and Biotechnology Research (IBBR) is proud to announce that Dr. Shunyuan Xiao, IBBR Fellow and Professor in the University of Maryland’s Department of Plant Sciences and Landscape Architecture, has received a five-year, $2 million Maximizing Investigators’ Research Award (MIRA, R35) from the National Institutes of Health...
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IBBR Postdoc Takes 3rd Place in Flash Talk Competition at UMD’s Postdoctoral Research Symposium
Dr. Patrick Keating, a postdoctoral researcher in Dr. Jaekyun Jeon’s laboratory, earned 3rd place in the Flash Talk Competition at the University of Maryland’s 2025 Postdoctoral Research Symposium! The symposium’s second annual event showcased the breadth of postdoctoral research across the University System of Maryland, providing a dynamic platform for...
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New Term ‘Translon’ Proposed to Standardize Genetic Technology
A recent publication in Nature Methods introduced a new term, ‘translon,’ to denote any region of genetic code that is translated. The article, entitled "Translon: a single term for translated regions,” was co-authored by an international team of researchers including Dr. Jonathan Dinman, Director of IBBR.
About IBBR
IBBR is a joint research enterprise of the University of Maryland, College Park, the University of Maryland, Baltimore, and the National Institute of Standards and Technology.
IBBR leverages state-of-art integrative methods for bioanalytical, biophysical and structural characterization of biomolecules: cryo-electron microscopy, nuclear magnetic resonance, x-ray crystallography, small angle neutron and x-ray scattering and mass spectrometry.
IBBR researchers seek to advance therapeutic development, biomanufacturing, and state-of-the-art measurement technologies, to support accelerated delivery of safe and effective medicines to the public.
IBBR is a major initiative and supported in part by the University of Maryland Strategic Partnership: MPowering the State (MPower) , an initiative designed to achieve innovation and impact through collaboration.
Connecting
IBBR Commons
Sophisticated state-of-the-art instrumentation and facilities, and in-house expertise located in shared space and dedicated to advance research, support collaboration and foster innovation of methods. Instrumentation and facilities include tools for high-resolution structural biology, bioanalytical and biophysical measurement, protein engineering and cell culture, advanced computation including artificial intelligence and deep learning methods, and general laboratory services. These capabilities and advanced training are available to IBBR scientists and collaborators.
IBBR Postdoc Program
The IBBR Postdoc Program (IPP) focuses on collaborative research involving basic science and technology development that advances therapeutic development, vaccine development, and biomanufacturing. IPP Fellow project teams are designed with a combination of the IPP Fellow career goals and priorities of project mentors who can be from academic, government, and/or industrial laboratories throughout the University of Maryland, NIST and the I-270 corridor.
NMRPipe
IBBR is home to NMRPipe, a popular collection of programs and scripts for manipulating multidimensional Nuclear Magnetic Resonance (NMR) data. The use of NMRPipe is noted in roughly 40% of all NMR structures accepted into the Protein Data Bank.
Upcoming Events
NIST Group Meeting: Kinlin Chao
Wednesday, November 19, 2025 - 11:00am
Seminar: Alexandra Kent, UC Berkeley
Monday, December 1, 2025 - 11:00am
BMD Staff Seminar S. Hilburg/ Z. Goecker, .03/.04
Tuesday, December 2, 2025 - 11:00am
Recent Publications
Progress and Bottlenecks for Deep Learning in Computational Structure Biology: CASP Round XVI.
CASP16 is the most recent in a series of community experiments to rigorously assess the state of the art in areas of computational structural biology. The field has advanced enormously in recent...
Effect of spatial dimensionality on the interplay between spinodal decomposition and wetting in multicomponent mixtures.
We utilize mesoscale Cahn-Hilliard-based phase-field simulations to explore the effects of spatial dimensionality on wetting-influenced phase separation in binary and ternary mixtures. A...
Modeling Alternative Conformational States in CASP16.
The CASP16 Ensemble Prediction experiment assessed advances in methods for modeling proteins, nucleic acids, and their complexes in multiple conformational states. Targets included systems with...
Polyphosphazene-Mediated Assembly of TLR4 and TLR7/8 Agonists Enables a Potent Nano-Adjuvant Delivery System for Hepatitis C Virus Vaccine Antigens.
Background: The quest for well-defined immunoadjuvants remains one of the highest priorities for the successful development of effective vaccines. Combination adjuvants, which are designed to...