IBBR Publications

Chandonia J-M, Adhikari A, Carraro M, Chhibber A, Cutting GR, Fu Y, Gasparini A, Jones DT, Kramer A, Kundu K, et al. 3Lessons from the CAGI-4 Hopkins clinical panel challenge. Hum Mutat. 2017 .

Brinson RG, Ghasriani H, Hodgson DJ, Adams KM, McEwen I, Freedberg DI, Chen K, Keire DA, Aubin Y, Marino JP. Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim. J Pharm Biomed Anal. 2017 ;141:229-233.

Borrman T, Cimons J, Cosiano M, Purcaro M, Pierce BG, Baker BM, Weng Z. ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes. Proteins. 2017 .

Martinez AP, Qamar B, Fuerst TR, Muro S, Andrianov AK. Biodegradable "Smart" Polyphosphazenes with Intrinsic Multi-Functionality as Intracellular Protein Delivery Vehicles. Biomacromolecules. 2017 .

Zang F, Chu S, Gerasopoulos K, Culver JN, Ghodssi R. Biofabrication of Tobacco mosaic virus-nanoscaffolded supercapacitors via temporal capillary microfluidics. Nanotechnology. 2017 ;28(26):265301.

Pal LR, Kundu K, Yin Y, Moult J. CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease. Hum Mutat. 2017 .

Pal LR, Kundu K, Yin Y, Moult J. CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants. Hum Mutat. 2017 .

Zang F, Gerasopoulos K, Brown AD, Culver JN, Ghodssi R. Capillary microfluidics-assembled virus-like particle bio-nano-receptor interfaces for label-free biosensing. ACS Appl Mater Interfaces. 2017 .

Quigley J, V Hughitt K, Velikovsky CA, Mariuzza RA, El-Sayed NM, Briken V. The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis. MBio. 2017 ;8(2).

Mazur SJ, Gallagher ES, Debnath S, Durell SR, Anderson KW, Jenkins LMMiller, Appella E, Hudgens JW. Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry. Biochemistry [Internet]. 2017 . Available from: http://pubs.acs.org/doi/abs/10.1021/acs.biochem.6b01220

Wu H-C, Quan DN, Tsao C-Y, Liu Y, Terrell JL, Luo X, Yang J-C, Payne GF, Bentley WE. Cover Image, Volume 114, Number 1, January 2017. Biotechnol Bioeng. 2017 ;114(1):i.

Häcker I, Harrell RA, Eichner G, Pilitt KL, O'Brochta DA, Handler AM, Schetelig MF. Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti. Sci Rep. 2017 ;7:43883.

Pidugu LSwarna Muk, Neu H, Wong TLok, Pozharski E, Molloy JL, Michel SLJ, Toth EA. Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site. Acta Crystallogr D Struct Biol. 2017 ;73(Pt 4):340-348.

Mast N, Anderson KW, Lin JB, Li Y, Turko IV, Tatsuoka C, Bjorkhem I, Pikuleva IA. Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum. J Biol Chem. 2017 .

Kundu K, Pal LR, Yin Y, Moult J. Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge. Hum Mutat. 2017 .

Tschirhart T, Kim E, Mckay R, Ueda H, Wu H-C, Pottash AEli, Zargar A, Negrete A, Shiloach J, Payne GF, et al. Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling. Nat Commun. 2017 ;8:14030.

Hwang IYoung, Koh E, Wong A, March JC, Bentley WE, Lee YSeng, Chang MWook. Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models. Nat Commun. 2017 ;8:15028.

Garnacho C, Dhami R, Solomon M, Schuchman EH, Muro S. Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice. Mol Ther. 2017 .

Yin Y, Kundu K, Pal LR, Moult J. Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges. Hum Mutat. 2017 .

Ragaliauskas T, Mickevicius M, Rakovska B, Penkauskas T, Vanderah DJ, Heinrich F, Valincius G. Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles. Biochim Biophys Acta. 2017 .

Burkhart BW, uboňová LČ, Heider MR, Kelman Z, Reeve JN, Santangelo TJ. The GAN exonuclease, or the flap endonuclease Fen1 and RNase HII are necessary for viability of Thermococcus kodakarensis. J Bacteriol. 2017 .

Chao KL, Kulakova L, Herzberg O. Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proc Natl Acad Sci U S A. 2017 ;114(7):E1128-E1137.

Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang C-I, Lei L, J Fels M, et al. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 2017 ;169(5):891-904.e15.

Mast N, Anderson KW, Johnson KM, Phan TTN, F Guengerich P, Pikuleva IA. In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds. J Biol Chem. 2017 .

Romasanta PN, Curto LM, Sarratea MB, Truant SNoli, Antonoglou MB, Lynch MJFernánd, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL. Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules. Biochem J. 2017 ;474(1):179-194.