Found 2066 results
3Lessons from the CAGI-4 Hopkins clinical panel challenge. Hum Mutat. 2017 .
Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim. J Pharm Biomed Anal. 2017 ;141:229-233..
ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes. Proteins. 2017 ..
Biodegradable "Smart" Polyphosphazenes with Intrinsic Multi-Functionality as Intracellular Protein Delivery Vehicles. Biomacromolecules. 2017 ..
Biofabrication of Tobacco mosaic virus-nanoscaffolded supercapacitors via temporal capillary microfluidics. Nanotechnology. 2017 ;28(26):265301..
CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease. Hum Mutat. 2017 ..
CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants. Hum Mutat. 2017 ..
Capillary microfluidics-assembled virus-like particle bio-nano-receptor interfaces for label-free biosensing. ACS Appl Mater Interfaces. 2017 ..
The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis. MBio. 2017 ;8(2)..
Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry. Biochemistry [Internet]. 2017 . Available from: http://pubs.acs.org/doi/abs/10.1021/acs.biochem.6b01220.
Cover Image, Volume 114, Number 1, January 2017. Biotechnol Bioeng. 2017 ;114(1):i..
Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti. Sci Rep. 2017 ;7:43883..
Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site. Acta Crystallogr D Struct Biol. 2017 ;73(Pt 4):340-348..
Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum. J Biol Chem. 2017 ..
Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge. Hum Mutat. 2017 ..
Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling. Nat Commun. 2017 ;8:14030.
Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models. Nat Commun. 2017 ;8:15028..
Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice. Mol Ther. 2017 ..
Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges. Hum Mutat. 2017 ..
Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles. Biochim Biophys Acta. 2017 ..
The GAN exonuclease, or the flap endonuclease Fen1 and RNase HII are necessary for viability of Thermococcus kodakarensis. J Bacteriol. 2017 ..
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proc Natl Acad Sci U S A. 2017 ;114(7):E1128-E1137..
Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 2017 ;169(5):891-904.e15.
In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds. J Biol Chem. 2017 ..