IBBR Publications

Mackerell AD, Jo S, Lakkaraju SKaushik, Lind C, Yu W. Identification and characterization of fragment binding sites for allosteric ligand design using the site identification by ligand competitive saturation hotspots approach (SILCS-Hotspots). Biochim Biophys Acta Gen Subj. 2020 ;1864(4):129519.

Andrianov AK, Marin A, Deng J, Fuerst TR. Protein-loaded soluble and nanoparticulate formulations of ionic polyphosphazenes and their interactions on molecular and cellular levels. Mater Sci Eng C Mater Biol Appl. 2020 ;106:110179.

Xu X, Godoy-Ruiz R, Adipietro KA, Peralta C, Ben-Hail D, Varney KM, Cook ME, Roth BM, Wilder PT, Cleveland T, et al. Structure of the cell-binding component of the binary toxin reveals a di-heptamer macromolecular assembly. Proc Natl Acad Sci U S A. 2020 .

Kelman LM, O'Dell WB, Kelman Z. Unwinding twenty years of the archaeal minichromosome maintenance helicase. J Bacteriol. 2020 .

Brinson RG, Marino JP. 2D J-correlated proton NMR experiments for structural fingerprinting of biotherapeutics. J Magn Reson. 2019 ;307:106581.

Urbanowicz RA, Wang R, Schiel JE, Keck Z-Y, Kerzic MC, Lau P, Rangarajan S, Garagusi KJ, Tan L, Guest JD, et al. Antigenicity and Immunogenicity of Differentially Glycosylated HCV E2 Envelope Proteins Expressed in Mammalian and Insect Cells. J Virol. 2019 .

Lei L, Tran K, Wang Y, Steinhardt JJ, Xiao Y, Chiang C-I, Wyatt RT, Li Y. Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs. Front Microbiol. 2019 ;10:672.

Kasak L, Bakolitsa C, Hu Z, Yu C, Rine J, Dimster-Denk DF, Pandey G, De Baets G, Bromberg Y, Cao C, et al. Assessing Computational Predictions of the Phenotypic Effect of Cystathionine-beta-Synthase Variants. Hum Mutat. 2019 .

Nazario-Toole AE, Wu LP. Assessing the Cellular Immune Response of the Fruit Fly, Drosophila melanogaster, Using an In Vivo Phagocytosis Assay. J Vis Exp. 2019 ;(146).

Pejaver V, Babbi G, Casadio R, Folkman L, Katsonis P, Kundu K, Lichtarge O, Martelli PLuigi, Miller M, Moult J, et al. Assessment of methods for predicting the effects of PTEN and TPMT protein variants. Hum Mutat. 2019 .

Carraro M, Monzon AMiguel, Chiricosta L, Reggiani F, Aspromonte MCristina, Bellini M, Pagel K, Jiang Y, Radivojac P, Kundu K, et al. Assessment of patient clinical descriptions and pathogenic variants from gene panel sequences in the CAGI-5 intellectual disability challenge. Hum Mutat. 2019 .

Clark WT, Kasak L, Bakolitsa C, Hu Z, Andreoletti G, Babbi G, Bromberg Y, Casadio R, Dunbrack R, Folkman L, et al. Assessment of predicted enzymatic activity of alpha-N-acetylglucosaminidase (NAGLU) variants of unknown significance for CAGI 2016. Hum Mutat. 2019 .

Ueda H, Stephens K, Trivisa K, Bentley WE. Bacteria Floc, but Do They Flock? Insights from Population Interaction Models of Quorum Sensing. MBio. 2019 ;10(3).

Stephens K, Pozo M, Tsao C-Y, Hauk P, Bentley WE. Bacterial co-culture with cell signaling translator and growth controller modules for autonomously regulated culture composition. Nat Commun. 2019 ;10(1):4129.

Keck Z-Y, Pierce BG, Lau P, Lu J, Wang Y, Underwood A, Bull RA, Prentoe J, Velázquez-Moctezuma R, Walker MR, et al. Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design. PLoS Pathog. 2019 ;15(5):e1007772.

Kasak L, Hunter JM, Udani R, Bakolitsa C, Hu Z, Adhikari AN, Babbi G, Casadio R, Gough J, Guerrero RF, et al. CAGI SickKids challenges: Assessment of phenotype and variant predictions derived from clinical and genomic data of children with undiagnosed diseases. Hum Mutat. 2019 .

Wang Z, Tschirhart T, Schultzhaus Z, Kelly EE, Chen A, Oh E, Nag O, Glaser ER, Kim E, Lloyd PF, et al. Characterization and application of melanin produced by the fast-growing marine bacterium through heterologous biosynthesis. Appl Environ Microbiol. 2019 .

Swift SM, Etobayeva IV, Reid KP, Waters JJ, Oakley BB, Donovan DM, Nelson DC. Characterization of LysBC17, a Lytic Endopeptidase from . Antibiotics (Basel). 2019 ;8(3).

Leith EM, O'Dell WB, Ke N, McClung C, Berkmen M, Bergonzo C, Brinson RG, Kelman Z. Characterization of the internal translation initiation region in monoclonal antibodies expressed in Escherichia coli. J Biol Chem. 2019 .

Yang H, Gong Y, Zhang H, Etobayeva I, Miernikiewicz P, Luo D, Li X, Zhang X, Dabrowska K, Nelson DC, et al. ClyJ, a novel pneumococcal chimeric lysin with a CHAP catalytic domain. Antimicrob Agents Chemother. 2019 .

Marcos-Contreras OA, Brenner JS, Kiseleva RY, Zuluaga-Ramirez V, Greineder CF, Villa CH, Hood ED, Myerson JW, Muro S, Persidsky Y, et al. Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain. J Control Release. 2019 ;301:54-61.

Shang X, Nelson DC. Contributions of Net Charge on the PlyC Endolysin CHAP Domain. Antibiotics (Basel). 2019 ;8(2).

Villa F, Mackerell AD, Roux B, Simonson T. Correction to "Classical Drude Polarizable Force Field Model for Methyl Phosphate and Its Interactions with Mg". J Phys Chem A. 2019 .

Briggs KT, Taraban MB, Wang W, Y Yu B. Correction to: Nondestructive Quantitative Inspection of Drug Products Using Benchtop NMR Relaxometry-the Case of NovoMix® 30. AAPS PharmSciTech. 2019 ;20(5):214.

Li J, Maniar D, Qu X, Liu H, Tsao C-Y, Kim E, Bentley WE, Liu C, Payne GF. Coupling Self-Assembly Mechanisms to Fabricate Molecularly and Electrically Responsive Films. Biomacromolecules. 2019 .