IBBR Publications

Amcheslavsky A, Wallace AL, Ejemel M, Li Q, McMahon CT, Stoppato M, Giuntini S, Schiller ZA, Pondish JR, Toomey JR, et al. Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design. Sci Rep. 2021 ;11(1):2751.

Linden SB, Alreja AB, Nelson DC. Application of bacteriophage-derived endolysins to combat streptococcal disease: current State and perspectives. Curr Opin Biotechnol. 2021 ;68:213-220.

Telu KH, Marupaka R, Andriamaharavo NR, Simón-Manso Y, Liang Y, Mirokhin YA, Bukhari TH, Preston RJ, Kashi L, Kelman Z, et al. Creation and Filtering of a Recurrent Spectral Library of CHO Cell Metabolites and Media Components. Biotechnol Bioeng. 2021 .

Shahid S, Gao M, D Gallagher T, Pozharski E, Brinson RG, Keck Z-Y, Foung SKH, Fuerst TR, Mariuzza RA. Crystal Structure of a Bivalent Antibody Fab Fragment. J Mol Biol. 2021 ;433(2):166714.

Guest JD, Wang R, Elkholy KH, Chagas A, Chao KL, Cleveland TE, Kim YChang, Keck Z-Y, Marin A, Yunus AS, et al. Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer. Proc Natl Acad Sci U S A. 2021 ;118(3).

Parvaiz N, Ahmad F, Yu W, Mackerell AD, Azam SSikander. Discovery of beta-lactamase CMY-10 inhibitors for combination therapy against multi-drug resistant Enterobacteriaceae. PLoS One. 2021 ;16(1):e0244967.

Guest JD, Vreven T, Zhou J, Moal I, Jeliazkov JR, Gray JJ, Weng Z, Pierce BG. An expanded benchmark for antibody-antigen docking and affinity prediction reveals insights into antibody recognition determinants. Structure. 2021 .

Feng J, Li YLian, Wang DJuan, Ma YY, Cai XL, Xiao S, Wen Y. First Report of strain YL19 causing crown infection pockets in strawberry in Liaoning Province, China. Plant Dis. 2021 .

Y Yu B, Briggs KT, Taraban MB, Brinson RG, Marino JP. Grand Challenges in Pharmaceutical Research Series: Ridding the Cold Chain for Biologics. Pharm Res. 2021 ;38(1):3-7.

Valencia SM, Zacharia A, Marin A, Matthews RL, Wu C-K, Myers B, Sanders C, Difilippantonio S, Kirnbauer R, Roden RB, et al. Improvement of RG1-VLP vaccine performance in BALB/c mice by substitution of alhydrogel with the next generation polyphosphazene adjuvant PCEP. Hum Vaccin Immunother. 2021 :1-14.

Qamar B, Solomon M, Marin A, Fuerst TR, Andrianov AK, Muro S. Intracellular Delivery of Active Proteins by Polyphosphazene Polymers. Pharmaceutics. 2021 ;13(2).

Marin A, Chowdhury A, Valencia SM, Zacharia A, Kirnbauer R, Roden RBS, Pinto LA, Shoemaker RH, Marshall JD, Andrianov AK. Next generation polyphosphazene immunoadjuvant: Synthesis, self-assembly and in vivo potency with human papillomavirus VLPs-based vaccine. Nanomedicine. 2021 ;33:102359.

Hu Y, Cheng Y, Yu X, Liu J, Yang L, Gao Y, Ke G, Zhou M, Mu B, Xiao S, et al. Overexpression of two CDPKs from wild Chinese grapevine enhances powdery mildew resistance in Vitis vinifera and Arabidopsis. New Phytol. 2021 .

Ngo V, Li H, Mackerell AD, Allen TW, Roux B, Noskov S. Polarization Effects in Water-Mediated Selective Cation Transport across a Narrow Transmembrane Channel. J Chem Theory Comput. 2021 .

Wang Y, Howell KA, Brannan J, Agans KN, Turner HL, Wirchnianski AS, Kailasan S, Fusco M, Galkin A, Chiang C-I, et al. Prominent Neutralizing Antibody Response Targeting the Glycoprotein Subunit Interface Elicited by Immunization. J Virol. 2021 .

Yu Y, Kramer A, Venable RM, Simmonett AC, Mackerell AD, Klauda JB, Pastor RW, Brooks BR. Semi-automated Optimization of the CHARMM36 Lipid Force Field to Include Explicit Treatment of Long-Range Dispersion. J Chem Theory Comput. 2021 .

Solano-Gonzalez E, Coburn KM, Yu W, Wilson GM, Nurmemmedov E, Kesari S, Chang ET, Mackerell AD, Weber DJ, Carrier F. Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint. Nucleic Acids Res. 2021 .

Young BD, Yu W, Rodríguez DJVera, Varney KM, Mackerell AD, Weber DJ. Specificity of Molecular Fragments Binding to S100B versus S100A1 as Identified by NMR and Site Identification by Ligand Competitive Saturation (SILCS). Molecules. 2021 ;26(2).

Krueger S, Curtis JE, Scott DR, Grishaev A, Glenn G, Smith G, Ellingsworth L, Borisov O, Maynard EL. Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution. Mol Pharm. 2021 ;18(1):359-376.

Mousaei M, Kudaibergenova M, Mackerell AD, Noskov S. Assessing hERG1 Blockade from Bayesian Machine-Learning-Optimized Site Identification by Ligand Competitive Saturation Simulations. J Chem Inf Model. 2020 ;60(12):6489-6501.

Arbogast LW, Delaglio F, Brinson RG, Marino JP. Assessment of the Higher-Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis. Curr Protoc Protein Sci. 2020 ;100(1):e105.

Arbogast LW, Delaglio F, Brinson RG, Marino JP. Assessment of the Higher‐Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis. Current Protocols in Protein Science [Internet]. 2020 ;100(1). Available from: https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpps.105

Josey BP, Heinrich F, Silin VI, Lösche M. Association of Model Neurotransmitters with Lipid Bilayer Membranes. Biophys J. 2020 .

Weissman JL, Stoltzfus A, Westra ER, Johnson PLF. Avoidance of Self during CRISPR Immunization. Trends Microbiol. 2020 ;28(7):543-553.

Kognole AA, Aytenfisu AH, Mackerell AD. Balanced polarizable Drude force field parameters for molecular anions: phosphates, sulfates, sulfamates, and oxides. J Mol Model. 2020 ;26(6):152.