IBBR Publications

Found 2578 results
2017
Tschirhart T, Kim E, Mckay R, Ueda H, Wu H-C, Pottash AEli, Zargar A, Negrete A, Shiloach J, Payne GF, et al. Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling. Nat Commun. 2017 ;8:14030.
Hwang IYoung, Koh E, Wong A, March JC, Bentley WE, Lee YSeng, Chang MWook. Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models. Nat Commun. 2017 ;8:15028.
Garnacho C, Dhami R, Solomon M, Schuchman EH, Muro S. Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice. Mol Ther. 2017 .
Yin Y, Kundu K, Pal LR, Moult J. Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges. Hum Mutat. 2017 .
Huang J, Mei Y, König G, Simmonett AC, Pickard FC, Wu Q, Wang L-P, Mackerell AD, Brooks BR, Shao Y. An Estimation of Hybrid Quantum Mechanical Molecular Mechanical Polarization Energies for Small Molecules Using Polarizable Force-Field Approaches. J Chem Theory Comput. 2017 ;13(2):679-695.
E Raman P, Lakkaraju SKaushik, Denny RAldrin, Mackerell AD. Estimation of relative free energies of binding using pre-computed ensembles based on the single-step free energy perturbation and the site-identification by Ligand competitive saturation approaches. J Comput Chem. 2017 ;38(15):1238-1251.
Kryshtafovych A, Monastyrskyy B, Fidelis K, Moult J, Schwede T, Tramontano A. Evaluation of the template-based modeling in CASP12. Proteins. 2017 .
Cardenas MG, Oswald E, Yu W, Xue F, Mackerell AD, Melnick AM. The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target. Clin Cancer Res. 2017 ;23(4):885-893.
Ragaliauskas T, Mickevicius M, Rakovska B, Penkauskas T, Vanderah DJ, Heinrich F, Valincius G. Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles. Biochim Biophys Acta. 2017 .
Huang J, Mackerell AD. Force field development and simulations of intrinsically disordered proteins. Curr Opin Struct Biol. 2017 ;48:40-48.
Kwegyir-Afful AK, Murigi FN, Purushottamachar P, Ramamurthy VP, Martin MS, Njar VCO. Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice. Oncotarget. 2017 ;8(32):52381-52402.
Burkhart BW, uboňová LČ, Heider MR, Kelman Z, Reeve JN, Santangelo TJ. The GAN exonuclease, or the flap endonuclease Fen1 and RNase HII are necessary for viability of Thermococcus kodakarensis. J Bacteriol. 2017 .
Chao KL, Kulakova L, Herzberg O. Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proc Natl Acad Sci U S A. 2017 ;114(7):E1128-E1137.
Gehring AM, Astling DP, Matsumi R, Burkhart BW, Kelman Z, Reeve JN, Jones KL, Santangelo TJ. Genome Replication in Thermococcus kodakarensis Independent of Cdc6 and an Origin of Replication. Front Microbiol. 2017 ;8:2084.
Wang Y, O'Dell S, Turner HL, Chiang C-I, Lei L, Guenaga J, Wilson R, Martinez-Murillo P, Doria-Rose N, Ward AB, et al. HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate. J Virol. 2017 .
Garnacho C, Muro S. ICAM-1 targeting, intracellular trafficking, and functional activity of polymer nanocarriers coated with a fibrinogen-derived peptide for lysosomal enzyme replacement. J Drug Target. 2017 :1-10.
Manthe RL, Muro S. ICAM-1-Targeted Nanocarriers Attenuate Endothelial Release of Soluble ICAM-1, an Inflammatory Regulator. Bioeng Transl Med. 2017 ;2(1):109-119.
Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang C-I, Lei L, J Fels M, et al. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 2017 ;169(5):891-904.e15.
Mast N, Anderson KW, Johnson KM, Phan TTN, F Guengerich P, Pikuleva IA. In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds. J Biol Chem. 2017 .
Rhoads MK, Hauk P, Terrell J, Tsao C-Y, Oh H, Raghavan SR, Mansy SS, Payne GF, Bentley WE. Incorporating LsrK AI-2 Quorum Quenching Capability in a Functionalized Biopolymer Capsule. Biotechnol Bioeng. 2017 .
Subramanian S, Tolstaya EI, Winkler T, Bentley WE, Ghodssi R. An Integrated Microsystem for Real-Time Detection and Threshold-Activated Treatment of Bacterial Biofilms. ACS Appl Mater Interfaces. 2017 .
Winkler TE, Dietrich R, Kim E, Ben-Yoav H, Kelly DL, Payne GF, Ghodssi R. The interplay of electrode- and bio-materials in a redox-cycling-based clozapine sensor. Electrochem commun. 2017 ;79:33-36.
Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, Mackerell AD, Jiang C, Xue F. Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation. J Org Chem. 2017 ;82(7):3589-3596.
Romasanta PN, Curto LM, Sarratea MB, Truant SNoli, Antonoglou MB, Lynch MJFernánd, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL. Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules. Biochem J. 2017 ;474(1):179-194.
Solomon M, Muro S. Lysosomal Enzyme Replacement Therapies: Historical Development, Clinical Outcomes, and Future Perspectives. Adv Drug Deliv Rev. 2017 .