Found 2578 results
Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling. Nat Commun. 2017 ;8:14030.
Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models. Nat Commun. 2017 ;8:15028..
Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice. Mol Ther. 2017 ..
Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges. Hum Mutat. 2017 ..
An Estimation of Hybrid Quantum Mechanical Molecular Mechanical Polarization Energies for Small Molecules Using Polarizable Force-Field Approaches. J Chem Theory Comput. 2017 ;13(2):679-695..
Estimation of relative free energies of binding using pre-computed ensembles based on the single-step free energy perturbation and the site-identification by Ligand competitive saturation approaches. J Comput Chem. 2017 ;38(15):1238-1251..
Evaluation of the template-based modeling in CASP12. Proteins. 2017 ..
The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target. Clin Cancer Res. 2017 ;23(4):885-893..
Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles. Biochim Biophys Acta. 2017 ..
Force field development and simulations of intrinsically disordered proteins. Curr Opin Struct Biol. 2017 ;48:40-48..
Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice. Oncotarget. 2017 ;8(32):52381-52402..
The GAN exonuclease, or the flap endonuclease Fen1 and RNase HII are necessary for viability of Thermococcus kodakarensis. J Bacteriol. 2017 ..
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proc Natl Acad Sci U S A. 2017 ;114(7):E1128-E1137..
Genome Replication in Thermococcus kodakarensis Independent of Cdc6 and an Origin of Replication. Front Microbiol. 2017 ;8:2084..
HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate. J Virol. 2017 .
ICAM-1 targeting, intracellular trafficking, and functional activity of polymer nanocarriers coated with a fibrinogen-derived peptide for lysosomal enzyme replacement. J Drug Target. 2017 :1-10..
ICAM-1-Targeted Nanocarriers Attenuate Endothelial Release of Soluble ICAM-1, an Inflammatory Regulator. Bioeng Transl Med. 2017 ;2(1):109-119..
Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 2017 ;169(5):891-904.e15.
In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds. J Biol Chem. 2017 ..
Incorporating LsrK AI-2 Quorum Quenching Capability in a Functionalized Biopolymer Capsule. Biotechnol Bioeng. 2017 ..
An Integrated Microsystem for Real-Time Detection and Threshold-Activated Treatment of Bacterial Biofilms. ACS Appl Mater Interfaces. 2017 ..
The interplay of electrode- and bio-materials in a redox-cycling-based clozapine sensor. Electrochem commun. 2017 ;79:33-36..
Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation. J Org Chem. 2017 ;82(7):3589-3596..
Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules. Biochem J. 2017 ;474(1):179-194..
Lysosomal Enzyme Replacement Therapies: Historical Development, Clinical Outcomes, and Future Perspectives. Adv Drug Deliv Rev. 2017 ..