IBBR Publications

Found 2527 results
2016
Pierce BG, Keck Z-Y, Lau P, Fauvelle C, Gowthaman R, Baumert TF, Fuerst TR, Mariuzza RA, Foung SKH. Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design. Proc Natl Acad Sci U S A. 2016 .
Robalino J, Wu LP. Gutsy Microbes Fly High in the Antiviral War. Trends Microbiol. 2016 ;24(1):2-4.
Fauvelle C, Colpitts CC, Keck Z-Y, Pierce BG, Foung SKH, Baumert TF. Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies. Expert Rev Vaccines. 2016 :1-10.
Wang Y, Sundling C, Wilson R, O'Dell S, Chen Y, Dai K, Phad GE, Zhu J, Xiao Y, Mascola JR, et al. High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence. J Immunol. 2016 .
Schermerhorn KM, Tanner N, Kelman Z, Gardner AF. High-temperature single-molecule kinetic analysis of thermophilic archaeal MCM helicases. Nucleic Acids Res. 2016 .
Chen Y, Wilson R, O'Dell S, Guenaga J, Feng Y, Tran K, Chiang C-I, Arendt HE, DeStefano J, Mascola JR, et al. An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes. J Immunol. 2016 ;197(10):3982-3998.
Dai K, Khan SN, Wang Y, He L, Guenaga J, Ingale J, Sundling C, O'Dell S, McKee K, Phad G, et al. HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation. Sci Rep. 2016 ;6:20987.
Berkey R, Zhang Y, Ma X, King H, Zhang Q, Wang W, Xiao S. Homologues of the RPW8 resistance protein are localized to the extra-haustorial membrane that is likely synthesized de novo. Plant Physiol. 2016 .
Serrano D, Manthe RL, Paul E, Chadha R, Muro S. How carrier size and valency modulate receptor-mediated signaling: understanding the link between binding and endocytosis of ICAM-1-targeted carriers. Biomacromolecules. 2016 .
Blevins SJ, Pierce BG, Singh NK, Riley TP, Wang Y, Spear TT, Nishimura MI, Weng Z, Baker BM. How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire. Proc Natl Acad Sci U S A. 2016 .
Lapidus RG, Carter-Cooper BA, Sadowska M, Choi EYong, Wonodi O, Muvarak N, Natarajan K, Pidugu LS, Jaiswal A, Toth EA, et al. Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2. Pharmaceuticals (Basel). 2016 ;9(1).
Purushottamachar P, Kwegyir-Afful AK, Martin MS, Ramamurthy VP, Ramalingam S, Njar VCO. Identification of Novel Steroidal Androgen Receptor Degrading Agents Inspired by Galeterone 3β-Imidazole Carbamate. ACS Med Chem Lett. 2016 ;7(7):708-13.
Heinzl GA, Huang W, Yu W, Giardina BJ, Zhou Y, Mackerell AD, Wilks A, Xue F. Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa. J Med Chem. 2016 ;59(14):6929-42.
Purushottamachar P, Murigi FN, Njar VCO. Improved Procedures for Gram-Scale Synthesis of Galeterone 3β-Imidazole and Galeterone 3β-Pyridine Methoxylate, Potent Androgen Receptor/Mnk Degrading Agents. Org. Process Res. Dev. 2016 ;20(9).
Khan HM, Grauffel C, Broer R, Mackerell AD, Havenith RWA, Reuter N. Improving the Force Field Description of Tyrosine-Choline Cation-π Interactions: QM Investigation of Phenol-N(Me)4(+) Interactions. J Chem Theory Comput. 2016 ;12(11):5585-5595.
Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan JJ, et al. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Transl Med. 2016 .
Hauk P, Stephens K, Mckay R, Virgile CRyan, Ueda H, Ostermeier M, Ryu K-S, Sintim HO, Bentley WE. Insightful directed evolution of Escherichia coli quorum sensing promoter region of the lsrACDBFG operon: a tool for synthetic biology systems and protein expression. Nucleic Acids Res. 2016 ;44(21):10515-10525.
Ghaffarian R, Roki N, Abouzeid A, Vreeland W, Muro S. Intra- and trans-cellular delivery of enzymes by direct conjugation with non-multivalent anti-ICAM molecules. J Control Release. 2016 .
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. 2016 .
Buckner CM, Kardava L, Zhang X, Gittens K, J Justement S, Kovacs C, McDermott AB, Li Y, Sajadi MM, Chun T-W, et al. Maintenance of HIV-Specific Memory B-Cell Responses in Elite Controllers Despite Low Viral Burden. J Infect Dis. 2016 .
Anderson KW, Mast N, Hudgens JW, Lin JB, Turko IV, Pikuleva IA. Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity. J Biol Chem. 2016 ;291(22):11876-86.
Gallagher ES, Hudgens JW. Mapping Protein-Ligand Interactions with Proteolytic Fragmentation, Hydrogen/Deuterium Exchange-Mass Spectrometry. Methods Enzymol. 2016 ;566:357-404.
Graff SM, Bentley WE. Mathematical model of LsrR-binding and derepression in Escherichia coli K12. J Bioinform Comput Biol. 2016 :1650039.
Meffre E, Louie A, Bannock J, J Y Kim L, Ho J, Frear CC, Kardava L, Wang W, Buckner CM, Wang Y, et al. Maturational characteristics of HIV-specific antibodies in viremic individuals. JCI Insight. 2016 ;1(3).
Barros M, Heinrich F, Datta SAK, Rein A, Karageorgos I, Nanda H, Lösche M. Membrane Binding of HIV-1 MA Protein: Dependence on Bilayer Composition and Protein Lipidation. J Virol. 2016 .