Publications
T Cell Receptor Genotype and Ubash3a Determine Susceptibility to Rat Autoimmune Diabetes.
Mordes JP, Cort L, Liu Z, Eberwine R, Blankenhorn EP, Pierce BG, Mordes JP, Cort L, Liu Z, Eberwine R, Blankenhorn EP, Pierce BG. 2021. T Cell Receptor Genotype and <i>Ubash3a</i> Determine Susceptibility to Rat Autoimmune Diabetes. Genes 12(6): . DOI: 10.3390/genes12060852
Electronic signals are electrogenetically relayed to control cell growth and co-culture composition.
Stephens K, Zakaria FR, VanArsdale E, Payne GF, Bentley WE, Stephens K, Zakaria FR, VanArsdale E, Payne GF, Bentley WE. 2021. Electronic signals are electrogenetically relayed to control cell growth and co-culture composition. Metabolic engineering communications 13: e00176. DOI: 10.1016/j.mec.2021.e00176
Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections.
Billingsley PF, George KI, Eappen AG, Harrell RA, Alford R, Li T, Chakravarty S, Sim BKL, Hoffman SL, O'Brochta DA, Billingsley PF, George KI, Eappen AG, Harrell RA, Alford R, Li T, Chakravarty S, Sim BKL, Hoffman SL, O'Brochta DA. 2021. Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections. Malaria journal 20(1): 284. DOI: 10.1186/s12936-021-03818-8
Principal Component Analysis of 1D 1H Diffusion Edited NMR Spectra of Protein Therapeutics.
Elliott KW, Delaglio F, Wikström M, Marino JP, Arbogast LW, Elliott KW, Delaglio F, Wikström M, Marino JP, Arbogast LW. 2021. Principal Component Analysis of 1D 1H Diffusion Edited NMR Spectra of Protein Therapeutics. Journal of pharmaceutical sciences 110(10): 3385-3394. DOI: 10.1016/j.xphs.2021.06.027
Mediated Electrochemical Probing: A Systems-Level Tool for Redox Biology.
Zhao Z, Ozcan EE, VanArsdale E, Li J, Kim E, Sandler AD, Kelly DL, Bentley WE, Payne GF, Zhao Z, Ozcan EE, VanArsdale E, Li J, Kim E, Sandler AD, Kelly DL, Bentley WE, Payne GF. 2021. Mediated Electrochemical Probing: A Systems-Level Tool for Redox Biology. ACS chemical biology 16(7): 1099-1110. DOI: 10.1021/acschembio.1c00267
1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23-225).
Roth BM, DePalma RM, Cook ME, Varney KM, Weber DJ, Ogretmen B, Roth BM, DePalma RM, Cook ME, Varney KM, Weber DJ, Ogretmen B. 2021. 1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23-225). Biomolecular NMR assignments 15(2): 383-387. DOI: 10.1007/s12104-021-10034-7
Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption.
Comert F, Heinrich F, Chowdhury A, Schoeneck M, Darling C, Anderson KW, Libardo MDJ, Angeles-Boza AM, Silin V, Cotten ML, et al. 2021. Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption. Scientific reports 11(1): 12620. DOI: 10.1038/s41598-021-91670-w
MecCog: A knowledge representation framework for genetic disease mechanism.
Kundu K, Darden L, Moult J, Kundu K, Darden L, Moult J. 2021. MecCog: A knowledge representation framework for genetic disease mechanism. Bioinformatics (Oxford, England) : . DOI: 10.1093/bioinformatics/btab432
Inspecting Insulin Products Using Water Proton NMR. I. Noninvasive vs Invasive Inspection.
Taraban MB, Wang Y, Briggs KT, Yu YB, Taraban MB, Wang Y, Briggs KT, Yu YB. 2021. Inspecting Insulin Products Using Water Proton NMR. I. Noninvasive vs Invasive Inspection. Journal of diabetes science and technology : 19322968211023806. DOI: 10.1177/19322968211023806
Structural Insights into the Mechanism of Base Excision by MBD4.
Pidugu LS, Bright H, Lin WJ, Majumdar C, Van Ostrand RP, David SS, Pozharski E, Drohat AC, Pidugu LS, Bright H, Lin WJ, Majumdar C, Van Ostrand RP, David SS, Pozharski E, Drohat AC. 2021. Structural Insights into the Mechanism of Base Excision by MBD4. Journal of molecular biology 433(15): 167097. DOI: 10.1016/j.jmb.2021.167097
The emerging landscape of single-molecule protein sequencing technologies.
Alfaro JA, Bohländer P, Dai M, Filius M, Howard CJ, van Kooten XF, Ohayon S, Pomorski A, Schmid S, Aksimentiev A, et al. 2021. The emerging landscape of single-molecule protein sequencing technologies. Nature methods 18(6): 604-617. DOI: 10.1038/s41592-021-01143-1
Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin.
King H, Ajay Castro S, Pohane AA, Scholte CM, Fischetti VA, Korotkova N, Nelson DC, Dorfmueller HC, King H, Ajay Castro S, Pohane AA, Scholte CM, Fischetti VA, Korotkova N, Nelson DC, Dorfmueller HC. 2021. Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin. The Biochemical journal 478(12): 2385-2397. DOI: 10.1042/BCJ20210158
Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development.
Toth EA, Chagas A, Pierce BG, Fuerst TR, Toth EA, Chagas A, Pierce BG, Fuerst TR. 2021. Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development. Viruses 13(6): . DOI: 10.3390/v13061027
Immunopotentiating and Delivery Systems for HCV Vaccines.
Andrianov AK, Fuerst TR, Andrianov AK, Fuerst TR. 2021. Immunopotentiating and Delivery Systems for HCV Vaccines. Viruses 13(6): . DOI: 10.3390/v13060981
Structure-Based and Rational Design of a Hepatitis C Virus Vaccine.
Guest JD, Pierce BG, Guest JD, Pierce BG. 2021. Structure-Based and Rational Design of a Hepatitis C Virus Vaccine. Viruses 13(5): . DOI: 10.3390/v13050837
A method to improve quantitative radiotracing-based analysis of the in vivo biodistribution of drug carriers.
Roki N, Solomon M, Casta L, Bowers J, Getts RC, Muro S, Roki N, Solomon M, Casta L, Bowers J, Getts RC, Muro S. 2021. A method to improve quantitative radiotracing-based analysis of the in vivo biodistribution of drug carriers. Bioengineering & translational medicine 6(2): e10208. DOI: 10.1002/btm2.10208
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, et al. 2021. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. bioRxiv : the preprint server for biology : . DOI: 10.1101/2021.05.10.443524
A simple approach for reconstruction of non-uniformly sampled pseudo-3D NMR data for accurate measurement of spin relaxation parameters.
East KW, Delaglio F, Lisi GP, East KW, Delaglio F, Lisi GP. 2021. A simple approach for reconstruction of non-uniformly sampled pseudo-3D NMR data for accurate measurement of spin relaxation parameters. Journal of biomolecular NMR 75(6-7): 213-219. DOI: 10.1007/s10858-021-00369-7
Reprogramming Virus Coat Protein Carboxylate Interactions for the Patterned Assembly of Hierarchical Nanorods.
Brown AD, Chu S, Kappagantu M, Ghodssi R, Culver JN, Brown AD, Chu S, Kappagantu M, Ghodssi R, Culver JN. 2021. Reprogramming Virus Coat Protein Carboxylate Interactions for the Patterned Assembly of Hierarchical Nanorods. Biomacromolecules 22(6): 2515-2523. DOI: 10.1021/acs.biomac.1c00258
Supramolecular assembly of Toll-like receptor 7/8 agonist into multimeric water-soluble constructs enables superior immune stimulation in vitro and in vivo.
Andrianov AK, Marin A, Wang R, Karauzum H, Chowdhury A, Agnihotri P, Yunus AS, Mariuzza RA, Fuerst TR, Andrianov AK, Marin A, Wang R, Karauzum H, Chowdhury A, Agnihotri P, Yunus AS, Mariuzza RA, Fuerst TR. 2020. Supramolecular assembly of Toll-like receptor 7/8 agonist into multimeric water-soluble constructs enables superior immune stimulation <i>in vitro</i> and <i>in vivo</i>. ACS applied bio materials 3(5): 3187-3195. DOI: 10.1021/acsabm.0c00189