IBBR Publications

Found 2527 results
2017
Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang C-I, Lei L, J Fels M, et al. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 2017 ;169(5):891-904.e15.
Mast N, Anderson KW, Johnson KM, Phan TTN, F Guengerich P, Pikuleva IA. In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds. J Biol Chem. 2017 .
Rhoads MK, Hauk P, Terrell J, Tsao C-Y, Oh H, Raghavan SR, Mansy SS, Payne GF, Bentley WE. Incorporating LsrK AI-2 Quorum Quenching Capability in a Functionalized Biopolymer Capsule. Biotechnol Bioeng. 2017 .
Subramanian S, Tolstaya EI, Winkler T, Bentley WE, Ghodssi R. An Integrated Microsystem for Real-Time Detection and Threshold-Activated Treatment of Bacterial Biofilms. ACS Appl Mater Interfaces. 2017 .
Winkler TE, Dietrich R, Kim E, Ben-Yoav H, Kelly DL, Payne GF, Ghodssi R. The interplay of electrode- and bio-materials in a redox-cycling-based clozapine sensor. Electrochem commun. 2017 ;79:33-36.
Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, Mackerell AD, Jiang C, Xue F. Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation. J Org Chem. 2017 ;82(7):3589-3596.
Romasanta PN, Curto LM, Sarratea MB, Truant SNoli, Antonoglou MB, Lynch MJFernánd, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL. Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules. Biochem J. 2017 ;474(1):179-194.
Solomon M, Muro S. Lysosomal Enzyme Replacement Therapies: Historical Development, Clinical Outcomes, and Future Perspectives. Adv Drug Deliv Rev. 2017 .
Huang J, Simmonett AC, Pickard FC, MacKerell AD, Brooks BR. Mapping the Drude polarizable force field onto a multipole and induced dipole model. J Chem Phys. 2017 ;147(16):161702.
Cai B, Li B, Kiga N, Thusberg J, Bergquist T, Chen Y-C, Niknafs N, Carter H, Tokheim C, Beleva-Guthrie V, et al. Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges. Hum Mutat. 2017 .
Ben-Yoav H, Dykstra PH, Bentley WE, Ghodssi R. Microfluidic Arrayed Lab-On-A-Chip for Electrochemical Capacitive Detection of DNA Hybridization Events. Methods Mol Biol. 2017 ;1572:71-88.
Costello CM, Phillipsen MB, Hartmanis LM, Kwasnica MA, Chen V, Hackam D, Chang MW, Bentley WE, March JC. Microscale Bioreactors for in situ characterization of GI epithelial cell physiology. Sci Rep. 2017 ;7(1):12515.
Winkler TE, Lederer SL, Kim E, Ben-Yoav H, Kelly DL, Payne GF, Ghodssi R. Molecular processes in an electrochemical clozapine sensor. Biointerphases. 2017 ;12(2):02B401.
Arbogast L, Delaglio F, Schiel JE, Marino JP. Multivariate Analysis of 2D (1)H,(13)C methyl NMR Spectra of Monoclonal Antibody Therapeutics to Facilitate Assessment of Higher Order Structure. Anal Chem. 2017 .
Stoltzfus A, McCandlish DM. Mutational biases influence parallel adaptation. Mol Biol Evol. 2017 .
Cheung CSF, Anderson KW, Patel PM, Cade KL, Phinney KW, Turko IV. A new approach to quantification of mAb aggregates using peptide affinity probes. Sci Rep. 2017 ;7:42497.
Maciejewski MW, Schuyler AD, Gryk MR, Moraru II, Romero PR, Ulrich EL, Eghbalnia HR, Livny M, Delaglio F, Hoch JC. NMRbox: A Resource for Biomolecular NMR Computation. Biophys J. 2017 ;112(8):1529-1534.
Shah NG, Tulapurkar ME, Ramarathnam A, Brophy A, Martinez R, Hom K, Hodges T, Samadani R, Singh IS, Mackerell AD, et al. Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity. J Immunol. 2017 ;198(8):3296-3306.
Cayatte C, Marin A, Rajani GManohar, Schneider-Ohrum K, Bennett ASnell, Marshall JD, Andrianov AK. PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection. Mol Pharm. 2017 .
Carraro M, Minervini G, Giollo M, Bromberg Y, Capriotti E, Casadio R, Dunbrack R, Elefanti L, Fariselli P, Ferrari C, et al. Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI. Hum Mutat. 2017 .
Kulkarni P, Jolly MKumar, Jia D, Mooney SM, Bhargava A, Kagohara LT, Chen Y, Hao P, He Y, Veltri RW, et al. Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity. Proc Natl Acad Sci U S A. 2017 .
Lemkul JA, Mackerell AD. Polarizable Force Field for DNA Based on the Classical Drude Oscillator: I. Refinement Using Quantum Mechanical Base Stacking and Conformational Energetics. J Chem Theory Comput. 2017 ;13(5):2053-2071.
Lemkul JA, Mackerell AD. Polarizable Force Field for DNA Based on the Classical Drude Oscillator: II. Microsecond Molecular Dynamics Simulations of Duplex DNA. J Chem Theory Comput. 2017 ;13(5):2072-2085.
Williams LTD, Ofek G, Schätzle S, McDaniel JR, Lu X, Nicely NI, Wu L, Lougheed CS, Bradley T, Louder MK, et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol. 2017 ;2(7).
Shen Y, Roche J, Grishaev A, Bax A. Prediction of nearest neighbor effects on backbone torsion angles and NMR scalar coupling constants in disordered proteins. Protein Sci. 2017 .