IBBR Publications

Found 2564 results
Zargar A, Quan DN, Bentley WE. Enhancing Intercellular Coordination: Rewiring Quorum Sensing Networks for Increased Protein Expression through Autonomous Induction. ACS Synth Biol. 2016 .
Sarkar A, Yu W, Desai UR, Mackerell AD, Mosier PD. Estimating glycosaminoglycan-protein interaction affinity: water dominates the specific antithrombin-heparin interaction. Glycobiology. 2016 ;26(10):1041-1047.
Wu H-C, Cha HJoon, Bentley WE. Evaluating Baculovirus Infection Using Green Fluorescent Protein and Variants. Methods Mol Biol. 2016 ;1350:447-459.
Da Silva SM, Vang LK, Olson ND, Lund SP, Downey AS, Kelman Z, Salit ML, Lin NJ, Morrow JB. Evaluation of microbial qPCR workflows using engineered Saccharomyces cerevisiae. Biomol Detect Quantif. 2016 ;7:27-33.
Kim E, Liu Y, Ben-Yoav H, Winkler TE, Yan K, Shi X, Shen J, Kelly DL, Ghodssi R, Bentley WE, et al. Fusing Sensor Paradigms to Acquire Chemical Information: An Integrative Role for Smart Biopolymeric Hydrogels. Adv Healthc Mater. 2016 .
Kwegyir-Afful AK, Murigi FN, Purushottamachar P, Ramamurthy VP, Martin MS, Njar VCO. Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice. Oncotarget. 2016 .
Kwegyir-Afful AK, Bruno RD, Purushottamachar P, Murigi FN, Njar VCO. Galeterone and VNPT55 disrupts Mnk-eIF4E to inhibit prostate cancer cell migration and invasion. FEBS J. 2016 .
Wu H-C, March JC, Bentley WE. Gene Silencing in Insect Cells Using RNAi. Methods Mol Biol. 2016 ;1350:469-76.
Riley TP, Ayres CM, Hellman LM, Singh NK, Cosiano M, Cimons JM, Anderson MJ, Piepenbrink KH, Pierce BG, Weng Z, et al. A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces. Protein Eng Des Sel. 2016 .
Pierce BG, Keck Z-Y, Lau P, Fauvelle C, Gowthaman R, Baumert TF, Fuerst TR, Mariuzza RA, Foung SKH. Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design. Proc Natl Acad Sci U S A. 2016 .
Robalino J, Wu LP. Gutsy Microbes Fly High in the Antiviral War. Trends Microbiol. 2016 ;24(1):2-4.
Fauvelle C, Colpitts CC, Keck Z-Y, Pierce BG, Foung SKH, Baumert TF. Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies. Expert Rev Vaccines. 2016 :1-10.
Wang Y, Sundling C, Wilson R, O'Dell S, Chen Y, Dai K, Phad GE, Zhu J, Xiao Y, Mascola JR, et al. High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence. J Immunol. 2016 .
Schermerhorn KM, Tanner N, Kelman Z, Gardner AF. High-temperature single-molecule kinetic analysis of thermophilic archaeal MCM helicases. Nucleic Acids Res. 2016 .
Chen Y, Wilson R, O'Dell S, Guenaga J, Feng Y, Tran K, Chiang C-I, Arendt HE, DeStefano J, Mascola JR, et al. An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes. J Immunol. 2016 ;197(10):3982-3998.
Dai K, Khan SN, Wang Y, He L, Guenaga J, Ingale J, Sundling C, O'Dell S, McKee K, Phad G, et al. HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation. Sci Rep. 2016 ;6:20987.
Berkey R, Zhang Y, Ma X, King H, Zhang Q, Wang W, Xiao S. Homologues of the RPW8 resistance protein are localized to the extra-haustorial membrane that is likely synthesized de novo. Plant Physiol. 2016 .
Serrano D, Manthe RL, Paul E, Chadha R, Muro S. How carrier size and valency modulate receptor-mediated signaling: understanding the link between binding and endocytosis of ICAM-1-targeted carriers. Biomacromolecules. 2016 .
Blevins SJ, Pierce BG, Singh NK, Riley TP, Wang Y, Spear TT, Nishimura MI, Weng Z, Baker BM. How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire. Proc Natl Acad Sci U S A. 2016 .
Lapidus RG, Carter-Cooper BA, Sadowska M, Choi EYong, Wonodi O, Muvarak N, Natarajan K, Pidugu LS, Jaiswal A, Toth EA, et al. Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2. Pharmaceuticals (Basel). 2016 ;9(1).
Purushottamachar P, Kwegyir-Afful AK, Martin MS, Ramamurthy VP, Ramalingam S, Njar VCO. Identification of Novel Steroidal Androgen Receptor Degrading Agents Inspired by Galeterone 3β-Imidazole Carbamate. ACS Med Chem Lett. 2016 ;7(7):708-13.
Heinzl GA, Huang W, Yu W, Giardina BJ, Zhou Y, Mackerell AD, Wilks A, Xue F. Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa. J Med Chem. 2016 ;59(14):6929-42.
Purushottamachar P, Murigi FN, Njar VCO. Improved Procedures for Gram-Scale Synthesis of Galeterone 3β-Imidazole and Galeterone 3β-Pyridine Methoxylate, Potent Androgen Receptor/Mnk Degrading Agents. Org. Process Res. Dev. 2016 ;20(9).
Khan HM, Grauffel C, Broer R, Mackerell AD, Havenith RWA, Reuter N. Improving the Force Field Description of Tyrosine-Choline Cation-π Interactions: QM Investigation of Phenol-N(Me)4(+) Interactions. J Chem Theory Comput. 2016 ;12(11):5585-5595.
Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan JJ, et al. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Transl Med. 2016 .