Publications

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VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins in vitro and in vivo by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2.
Thankan RS, Thomas E, Purushottamachar P, Weber DJ, Ramamurthy VP, Huang W, Kane MA, Njar VCO, Thankan RS, Thomas E, Purushottamachar P, Weber DJ, Ramamurthy VP, Huang W, Kane MA, Njar VCO. 2023. VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins <i>in vitro</i> and <i>in vivo</i> by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2. Frontiers in oncology 13: 1240996. DOI: 10.3389/fonc.2023.1240996
Role of the Lactide:Glycolide Ratio in PLGA Nanoparticle Stability and Release under Lysosomal Conditions for Enzyme Replacement Therapy of Lysosomal Storage Disorders.
Del Moral M, Loeck M, Muntimadugu E, Vives G, Pham V, Pfeifer P, Battaglia G, Muro S, Del Moral M, Loeck M, Muntimadugu E, Vives G, Pham V, Pfeifer P, Battaglia G, Muro S. 2023. Role of the Lactide:Glycolide Ratio in PLGA Nanoparticle Stability and Release under Lysosomal Conditions for Enzyme Replacement Therapy of Lysosomal Storage Disorders. Journal of functional biomaterials 14(9): . DOI: 10.3390/jfb14090440
Role of Domain-Domain Interactions on the Self-Association and Physical Stability of Monoclonal Antibodies: Effect of pH and Salt.
Xu AY, Blanco MA, Castellanos MM, Meuse CW, Mattison K, Karageorgos I, Hatch HW, Shen VK, Curtis JE, Xu AY, Blanco MA, Castellanos MM, Meuse CW, Mattison K, Karageorgos I, Hatch HW, Shen VK, Curtis JE. 2023. Role of Domain-Domain Interactions on the Self-Association and Physical Stability of Monoclonal Antibodies: Effect of pH and Salt. The journal of physical chemistry. B : . DOI: 10.1021/acs.jpcb.3c03928
Neuroimaging in insomnia: Review and reconsiderations.
Aquino G, Schiel JE, Aquino G, Schiel JE. 2023. Neuroimaging in insomnia: Review and reconsiderations. Journal of sleep research : e14030. DOI: 10.1111/jsr.14030
Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Abbott KL, Ali A, Casalena D, Do BT, Ferreira R, Cheah JH, Soule CK, Deik A, Kunchok T, Schmidt DR, et al. 2023. Screening in serum-derived medium reveals differential response to compounds targeting metabolism. Cell chemical biology : . DOI: 10.1016/j.chembiol.2023.08.007
Combining SILCS and Artificial Intelligence for High-Throughput Prediction of the Passive Permeability of Drug Molecules.
Pandey P, MacKerell AD, Pandey P, MacKerell AD. 2023. Combining SILCS and Artificial Intelligence for High-Throughput Prediction of the Passive Permeability of Drug Molecules. Journal of chemical information and modeling : . DOI: 10.1021/acs.jcim.3c00514
Endosomal activation of the Clostridioides difficile binary toxin is Ca 2+ -dependent.
Abeyawardhane DL, Adipietro KA, Godoy-Ruiz R, Varney KM, Sevdalis SE, Nawaz IF, Spittel AX, Rustandi RR, Silin VI, des Georges A, et al. 2023. Endosomal activation of the <i>Clostridioides difficile</i> binary toxin is Ca 2+ -dependent. bioRxiv : the preprint server for biology : . DOI: 10.1101/2023.08.18.553786
Strategies for rapid production of crystallization quality coatomer WD40 domains.
Dey D, Hasan SS, Dey D, Hasan SS. 2023. Strategies for rapid production of crystallization quality coatomer WD40 domains. Protein expression and purification : 106358. DOI: 10.1016/j.pep.2023.106358
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Mishra AK, Shahid S, Karade SS, Agnihotri P, Kolesnikov A, Hasan SS, Mariuzza RA, Mishra AK, Shahid S, Karade SS, Agnihotri P, Kolesnikov A, Hasan SS, Mariuzza RA. 2023. CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure (London, England : 1993) : . DOI: 10.1016/j.str.2023.07.013
Revealing Redox Behavior of Molybdenum Disulfide and Its Application as Rechargeable Antioxidant Reservoir.
Kang M, Chai K, Lee S, Oh JH, Bae JS, Payne GF, Kang M, Chai K, Lee S, Oh JH, Bae JS, Payne GF. 2023. Revealing Redox Behavior of Molybdenum Disulfide and Its Application as Rechargeable Antioxidant Reservoir. ACS applied materials & interfaces : . DOI: 10.1021/acsami.3c08659
Particle Metrology Approach to Understanding How Storage Conditions Affect Long-Term Liposome Stability.
Lehman SE, Benkstein KD, Cleveland TE, Anderson KW, Carrier MJ, Vreeland WN, Lehman SE, Benkstein KD, Cleveland TE, Anderson KW, Carrier MJ, Vreeland WN. 2023. Particle Metrology Approach to Understanding How Storage Conditions Affect Long-Term Liposome Stability. Langmuir : the ACS journal of surfaces and colloids : . DOI: 10.1021/acs.langmuir.3c01270
Prospects for developing an Hepatitis C virus E1E2-based nanoparticle vaccine.
Toth EA, Andrianov AK, Fuerst TR, Toth EA, Andrianov AK, Fuerst TR. 2023. Prospects for developing an Hepatitis C virus E1E2-based nanoparticle vaccine. Reviews in medical virology : e2474. DOI: 10.1002/rmv.2474
Correction: Preventive Pharmacovigilance: timely and precise prevention of adverse events through person-level patient screening and dose-level product surveillance.
Yu YB, Briggs KT, Taraban MB, Yu YB, Briggs KT, Taraban MB. 2023. Correction: Preventive Pharmacovigilance: timely and precise prevention of adverse events through person-level patient screening and dose-level product surveillance. Pharmaceutical research : . DOI: 10.1007/s11095-023-03575-0
High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy.
Pirolli NH, Reus LSC, Mamczarz Z, Khan S, Bentley WE, Jay SM, Pirolli NH, Reus LSC, Mamczarz Z, Khan S, Bentley WE, Jay SM. 2023. High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy. Biotechnology and bioengineering : . DOI: 10.1002/bit.28522
Divalent ions as mediators of carbonylation in cardiac myosin binding protein C.
Bergonzo C, Aryal B, Rao VA, Bergonzo C, Aryal B, Rao VA. 2023. Divalent ions as mediators of carbonylation in cardiac myosin binding protein C. Journal of molecular graphics & modelling 124: 108576. DOI: 10.1016/j.jmgm.2023.108576