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Publications

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On the possibility of constructive neutral evolution.
Stoltzfus A. 1999. On the possibility of constructive neutral evolution. Journal of molecular evolution 49(2): 169-81.
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Chen CC, Herzberg O. 1999. Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp. Protein engineering 12(7): 573-9.
Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds.
Turko IV, Ballard SA, Francis SH, Corbin JD. 1999. Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds. Molecular pharmacology 56(1): 124-30.
Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate.
Huang K, Li Z, Jia Y, Dunaway-Mariano D, Herzberg O. 1999. Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate. Structure (London, England : 1993) 7(5): 539-48.
The structural basis of T cell activation by superantigens.
Li H, Llera A, Malchiodi EL, Mariuzza RA. 1999. The structural basis of T cell activation by superantigens. Annual review of immunology 17: 435-66.
Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes.
Andersen PS, Lavoie PM, Sékaly RP, Churchill H, Kranz DM, Schlievert PM, Karjalainen K, Mariuzza RA. 1999. Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes. Immunity 10(4): 473-83.
Protein backbone angle restraints from searching a database for chemical shift and sequence homology.
Cornilescu G, Delaglio F, Bax A. 1999. Protein backbone angle restraints from searching a database for chemical shift and sequence homology. Journal of biomolecular NMR 13(3): 289-302.
Structural consequences of the active site substitution Cys181 ==> Ser in metallo-beta-lactamase from Bacteroides fragilis.
Li Z, Rasmussen BA, Herzberg O. 1999. Structural consequences of the active site substitution Cys181 ==> Ser in metallo-beta-lactamase from Bacteroides fragilis. Protein science : a publication of the Protein Society 8(1): 249-52.
Hydrogen bonding and equilibrium protium-deuterium fractionation factors in the immunoglobulin G binding domain of protein G.
Khare D, Alexander P, Orban J. 1999. Hydrogen bonding and equilibrium protium-deuterium fractionation factors in the immunoglobulin G binding domain of protein G. Biochemistry 38(13): 3918-25.
Enzymatic grafting of a natural product onto chitosan to confer water solubility under basic conditions
Kumar G, Smith PJ, Payne GF. 1999. Enzymatic grafting of a natural product onto chitosan to confer water solubility under basic conditions Biotechnology and bioengineering 63(2): 154-65.
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen.
Zhang G, Gibbs E, Kelman Z, O'Donnell M, Hurwitz J. 1999. Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen. Proceedings of the National Academy of Sciences of the United States of America 96(5): 1869-74.
Biophysical characterization of a designed TMV coat protein mutant, R46G, that elicits a moderate hypersensitivity response in Nicotiana sylvestris.
Toedt JM, Braswell EH, Schuster TM, Yphantis DA, Taraporewala ZF, Culver JN. 1999. Biophysical characterization of a designed TMV coat protein mutant, R46G, that elicits a moderate hypersensitivity response in Nicotiana sylvestris. Protein science : a publication of the Protein Society 8(2): 261-70.
Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase.
Yuzhakov A, Kelman Z, O'Donnell M. 1999. Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase. Cell 96(1): 153-63.
The internal workings of a DNA polymerase clamp-loading machine.
Turner J, Hingorani MM, Kelman Z, O'Donnell M. 1999. The internal workings of a DNA polymerase clamp-loading machine. The EMBO journal 18(3): 771-83.
Determinants of side chain conformational preferences in protein structures.
Samudrala R, Moult J. 1998. Determinants of side chain conformational preferences in protein structures. Protein engineering 11(11): 991-7.