Publications

High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides.
Borrman T, Pierce BG, Vreven T, Baker BM, Weng Z, Borrman T, Pierce BG, Vreven T, Baker BM, Weng Z. 2020. High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides. Bioinformatics (Oxford, England) : . DOI: 10.1093/bioinformatics/btaa1050
Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution.
Krueger S, Curtis JE, Scott DR, Grishaev A, Glenn G, Smith G, Ellingsworth L, Borisov O, Maynard EL, Krueger S, Curtis JE, Scott DR, Grishaev A, Glenn G, Smith G, Ellingsworth L, Borisov O, Maynard EL. 2021. Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution. Molecular pharmaceutics 18(1): 359-376. DOI: 10.1021/acs.molpharmaceut.0c00986
Polyphosphazenes enable durable, hemocompatible, highly efficient antibacterial coatings.
Albright V, Penarete-Acosta D, Stack M, Zheng J, Marin A, Hlushko H, Wang H, Jayaraman A, Andrianov AK, Sukhishvili SA, Albright V, Penarete-Acosta D, Stack M, Zheng J, Marin A, Hlushko H, Wang H, Jayaraman A, Andrianov AK, Sukhishvili SA. 2021. Polyphosphazenes enable durable, hemocompatible, highly efficient antibacterial coatings. Biomaterials 268: 120586. DOI: 10.1016/j.biomaterials.2020.120586
Sand Fly (Phlebotomus papatasi) Embryo Microinjection for CRISPR/Cas9 Mutagenesis.
Louradour I, Ghosh K, Inbar E, Sacks DL, Aluvihare C, Harrell RA, Louradour I, Ghosh K, Inbar E, Sacks DL, Aluvihare C, Harrell RA. 2020. Sand Fly (Phlebotomus papatasi) Embryo Microinjection for CRISPR/Cas9 Mutagenesis. Journal of visualized experiments : JoVE (165): . DOI: 10.3791/61924
Polyphosphazene immunoadjuvants: Historical perspective and recent advances.
Andrianov AK, Langer R, Andrianov AK, Langer R. 2021. Polyphosphazene immunoadjuvants: Historical perspective and recent advances. Journal of controlled release : official journal of the Controlled Release Society 329: 299-315. DOI: 10.1016/j.jconrel.2020.12.001
Sequencing and analysis of gerbera daisy leaf transcriptomes reveal disease resistance and susceptibility genes differentially expressed and associated with powdery mildew resistance.
Bhattarai K, Conesa A, Xiao S, Peres NA, Clark DG, Parajuli S, Deng Z, Bhattarai K, Conesa A, Xiao S, Peres NA, Clark DG, Parajuli S, Deng Z. 2020. Sequencing and analysis of gerbera daisy leaf transcriptomes reveal disease resistance and susceptibility genes differentially expressed and associated with powdery mildew resistance. BMC plant biology 20(1): 539. DOI: 10.1186/s12870-020-02742-4
Crystal Structure of a Bivalent Antibody Fab Fragment.
Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA, Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA. 2021. Crystal Structure of a Bivalent Antibody Fab Fragment. Journal of molecular biology 433(2): 166714. DOI: 10.1016/j.jmb.2020.11.013
Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo.
Maranto C, Udhane V, Jia J, Verma R, Müller-Newen G, LaViolette PS, Pereckas M, Sabharwal L, Terhune S, Pattabiraman N, et al. 2020. Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo. Cancers 12(11): . DOI: 10.3390/cancers12113412
Quantitative Proteomic Analysis of Biogenesis-Based Classification for Extracellular Vesicles.
Zhang L, Parot J, Hackley VA, Turko IV, Zhang L, Parot J, Hackley VA, Turko IV. 2020. Quantitative Proteomic Analysis of Biogenesis-Based Classification for Extracellular Vesicles. Proteomes 8(4): . DOI: 10.3390/proteomes8040033
COVID-19 reopening strategies at the county level in the face of uncertainty: Multiple Models for Outbreak Decision Support.
Shea K, Borchering RK, Probert WJM, Howerton E, Bogich TL, Li S, van Panhuis WG, Viboud C, Aguás R, Belov A, et al. 2020. COVID-19 reopening strategies at the county level in the face of uncertainty: Multiple Models for Outbreak Decision Support. medRxiv : the preprint server for health sciences : . DOI: 10.1101/2020.11.03.20225409
Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs).
He Y, Agnihotri P, Rangarajan S, Chen Y, Kerzic MC, Ma B, Nussinov R, Mariuzza RA, Orban J, He Y, Agnihotri P, Rangarajan S, Chen Y, Kerzic MC, Ma B, Nussinov R, Mariuzza RA, Orban J. 2020. Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs). Journal of molecular biology 432(24): 166697. DOI: 10.1016/j.jmb.2020.10.031
Conformational gating, dynamics and allostery in human monoacylglycerol lipase.
Tyukhtenko S, Ma X, Rajarshi G, Karageorgos I, Anderson KW, Hudgens JW, Guo JJ, Nasr ML, Zvonok N, Vemuri K, et al. 2020. Conformational gating, dynamics and allostery in human monoacylglycerol lipase. Scientific reports 10(1): 18531. DOI: 10.1038/s41598-020-75497-5
Redox Electrochemistry to Interrogate and Control Biomolecular Communication.
VanArsdale E, Pitzer J, Payne GF, Bentley WE, VanArsdale E, Pitzer J, Payne GF, Bentley WE. 2020. Redox Electrochemistry to Interrogate and Control Biomolecular Communication. iScience 23(9): 101545. DOI: 10.1016/j.isci.2020.101545
ANNEXIN 8 negatively regulates RPW8.1-mediated cell death and disease resistance in Arabidopsis.
Zhao ZX, Xu YJ, Lei Y, Li Q, Zhao JQ, Li Y, Fan J, Xiao S, Wang WM, Zhao ZX, Xu YJ, Lei Y, Li Q, Zhao JQ, Li Y, Fan J, Xiao S, Wang WM. 2021. ANNEXIN 8 negatively regulates RPW8.1-mediated cell death and disease resistance in Arabidopsis. Journal of integrative plant biology 63(2): 378-392. DOI: 10.1111/jipb.13025
1HN, 13C, and 15N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757-876).
Cook ME, Varney KM, Godoy-Ruiz R, Weber DJ, Cook ME, Varney KM, Godoy-Ruiz R, Weber DJ. 2021. 1HN, 13C, and 15N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757-876). Biomolecular NMR assignments 15(1): 35-39. DOI: 10.1007/s12104-020-09979-y
Characterization of the Bacteriophage-Derived Endolysins PlySs2 and PlySs9 with In Vitro Lytic Activity against Bovine Mastitis Streptococcus uberis.
Vander Elst N, Linden SB, Lavigne R, Meyer E, Briers Y, Nelson DC, Vander Elst N, Linden SB, Lavigne R, Meyer E, Briers Y, Nelson DC. 2020. Characterization of the Bacteriophage-Derived Endolysins PlySs2 and PlySs9 with In Vitro Lytic Activity against Bovine Mastitis <i>Streptococcus uberis</i>. Antibiotics (Basel, Switzerland) 9(9): . DOI: 10.3390/antibiotics9090621
Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7.
Greenfield J, Shang X, Luo H, Zhou Y, Linden SB, Heselpoth RD, Leiman PG, Nelson DC, Herzberg O, Greenfield J, Shang X, Luo H, Zhou Y, Linden SB, Heselpoth RD, Leiman PG, Nelson DC, Herzberg O. 2020. Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7. Scientific reports 10(1): 15402. DOI: 10.1038/s41598-020-72373-0
A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer.
Mohanty A, Nam A, Pozhitkov A, Yang L, Srivastava S, Nathan A, Wu X, Mambetsariev I, Nelson M, Subbalakshmi AR, et al. 2020. A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer. iScience 23(9): 101496. DOI: 10.1016/j.isci.2020.101496
Chemical shifts-based similarity restraints improve accuracy of RNA structures determined via NMR.
Lawrence C, Grishaev A, Lawrence C, Grishaev A. 2020. Chemical shifts-based similarity restraints improve accuracy of RNA structures determined via NMR. RNA (New York, N.Y.) 26(12): 2051-2061. DOI: 10.1261/rna.074617.119
CoV3D: a database of high resolution coronavirus protein structures.
Gowthaman R, Guest JD, Yin R, Adolf-Bryfogle J, Schief WR, Pierce BG, Gowthaman R, Guest JD, Yin R, Adolf-Bryfogle J, Schief WR, Pierce BG. 2021. CoV3D: a database of high resolution coronavirus protein structures. Nucleic acids research 49(D1): D282-D287. DOI: 10.1093/nar/gkaa731