Found 65 results
Filters: Author is Muro, Silvia [Clear All Filters]
Biodegradable "Smart" Polyphosphazenes with Intrinsic Multi-Functionality as Intracellular Protein Delivery Vehicles. Biomacromolecules. 2017 ..
Co-coating of receptor-targeted drug nanocarriers with anti-phagocytic moieties enhances specific tissue uptake versus non-specific phagocytic clearance. Biomaterials. 2017 ;147:14-25..
Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice. Mol Ther. 2017 ..
ICAM-1 targeting, intracellular trafficking, and functional activity of polymer nanocarriers coated with a fibrinogen-derived peptide for lysosomal enzyme replacement. J Drug Target. 2017 :1-10..
ICAM-1-Targeted Nanocarriers Attenuate Endothelial Release of Soluble ICAM-1, an Inflammatory Regulator. Bioeng Transl Med. 2017 ;2(1):109-119..
Lysosomal Enzyme Replacement Therapies: Historical Development, Clinical Outcomes, and Future Perspectives. Adv Drug Deliv Rev. 2017 ..
Targeting superoxide dismutase to endothelial caveolae profoundly alleviates inflammation caused by endotoxin. J Control Release. 2017 ;272:1-8..
Chitosan-Alginate Microcapsules Provide Gastric Protection and Intestinal Release of ICAM-1-Targeting Nanocarriers, Enabling GI Targeting In Vivo. Adv Funct Mater. 2016 ;26(20):3382-3393..
A Comparative Study on the Alterations of Endocytic Pathways in Multiple Lysosomal Storage Disorders. Mol Pharm. 2016 ..
How carrier size and valency modulate receptor-mediated signaling: understanding the link between binding and endocytosis of ICAM-1-targeted carriers. Biomacromolecules. 2016 ..
Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Transl Med. 2016 .
Intra- and trans-cellular delivery of enzymes by direct conjugation with non-multivalent anti-ICAM molecules. J Control Release. 2016 ..
Altered Clathrin-Independent Endocytosis in Type A Niemann-Pick Disease Cells and Rescue by ICAM-1-Targeted Enzyme Delivery. Mol Pharm. 2015 ;12(5):1366-76..
DNA-Based Drug Carriers: The Paradox of a Classical "Cargo" Material Becoming a Versatile "Carrier" to Overcome Barriers in Drug Delivery. Curr Pharm Des. 2015 ..
Editorial: Drug Delivery: Open Sesame Strategies for the One Thousand and One Body Barriers. Curr Pharm Des. 2015 ..
Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1. J Control Release. 2015 ;210:39-47..
Clathrin-Mediated Endocytosis Is Impaired in Type A-B Niemann-Pick Disease Model Cells and Can Be Restored by ICAM-1-Mediated Enzyme Replacement. Mol Pharm. 2014 ..
Combination-targeting to multiple endothelial cell adhesion molecules modulates binding, endocytosis, and in vivo biodistribution of drug nanocarriers and their therapeutic cargoes. J Control Release. 2014 ;188C:87-98..
Distinct Subcellular Trafficking Resulting from Monomeric vs Multimeric Targeting to Endothelial ICAM-1: Implications for Drug Delivery. Mol Pharm. 2014 ..
A DNA-Device that Mediates Selective Endosomal Escape and Intracellular Delivery of Drugs and Biologicals. Adv Funct Mater. 2014 ;24(19):2899-2906..
Enhancing biodistribution of therapeutic enzymes in vivo by modulating surface coating and concentration of ICAM-1-targeted nanocarriers. J Biomed Nanotechnol. 2014 ;10(2):345-54..
Open challenges in magnetic drug targeting. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 ..
Specific Binding, Uptake, and Transport of ICAM-1-Targeted Nanocarriers Across Endothelial and Subendothelial Cell Components of the Blood-Brain Barrier. Pharm Res. 2014 ..