Publications

Some measures of comparative performance in the three CASPs.
Venclovas C, Zemla A, Fidelis K, Moult J. 1999. Some measures of comparative performance in the three CASPs. Proteins Suppl 3: 231-7.
Processing and analysis of CASP3 protein structure predictions.
Zemla A, Venclovas C, Moult J, Fidelis K. 1999. Processing and analysis of CASP3 protein structure predictions. Proteins Suppl 3: 22-9.
Critical assessment of methods of protein structure prediction (CASP): round III.
Moult J, Hubbard T, Fidelis K, Pedersen JT. 1999. Critical assessment of methods of protein structure prediction (CASP): round III. Proteins Suppl 3: 2-6.
Studies of the molecular mechanism of discrimination between cGMP and cAMP in the allosteric sites of the cGMP-binding cGMP-specific phosphodiesterase (PDE5).
Turko IV, Francis SH, Corbin JD. 1999. Studies of the molecular mechanism of discrimination between cGMP and cAMP in the allosteric sites of the cGMP-binding cGMP-specific phosphodiesterase (PDE5). The Journal of biological chemistry 274(41): 29038-41.
Local electrostatic optimization in proteins.
Oliva MT, Moult J. 1999. Local electrostatic optimization in proteins. Protein engineering 12(9): 727-35.
Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH.
Kelman Z, Pietrokovski S, Hurwitz J. 1999. Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH. The Journal of biological chemistry 274(40): 28751-61.
The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity.
Kelman Z, Zuo S, Arroyo MP, Wang TS, Hurwitz J. 1999. The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity. Proceedings of the National Academy of Sciences of the United States of America 96(17): 9515-20.
On the possibility of constructive neutral evolution.
Stoltzfus A. 1999. On the possibility of constructive neutral evolution. Journal of molecular evolution 49(2): 169-81.
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Chen CC, Herzberg O. 1999. Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp. Protein engineering 12(7): 573-9.
Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds.
Turko IV, Ballard SA, Francis SH, Corbin JD. 1999. Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds. Molecular pharmacology 56(1): 124-30.
Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate.
Huang K, Li Z, Jia Y, Dunaway-Mariano D, Herzberg O. 1999. Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate. Structure (London, England : 1993) 7(5): 539-48.
The structural basis of T cell activation by superantigens.
Li H, Llera A, Malchiodi EL, Mariuzza RA. 1999. The structural basis of T cell activation by superantigens. Annual review of immunology 17: 435-66.
Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes.
Andersen PS, Lavoie PM, Sékaly RP, Churchill H, Kranz DM, Schlievert PM, Karjalainen K, Mariuzza RA. 1999. Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes. Immunity 10(4): 473-83.
Protein backbone angle restraints from searching a database for chemical shift and sequence homology.
Cornilescu G, Delaglio F, Bax A. 1999. Protein backbone angle restraints from searching a database for chemical shift and sequence homology. Journal of biomolecular NMR 13(3): 289-302.
Structural consequences of the active site substitution Cys181 ==> Ser in metallo-beta-lactamase from Bacteroides fragilis.
Li Z, Rasmussen BA, Herzberg O. 1999. Structural consequences of the active site substitution Cys181 ==> Ser in metallo-beta-lactamase from Bacteroides fragilis. Protein science : a publication of the Protein Society 8(1): 249-52.