Publications

Mutation bias shapes the spectrum of adaptive substitutions.
Cano AV, Rozhoňová H, Stoltzfus A, McCandlish DM, Payne JL, Cano AV, Rozhoňová H, Stoltzfus A, McCandlish DM, Payne JL. 2022. Mutation bias shapes the spectrum of adaptive substitutions. Proceedings of the National Academy of Sciences of the United States of America 119(7): . DOI: 10.1073/pnas.2119720119
Deep Neural Network Model to Predict the Electrostatic Parameters in the Polarizable Classical Drude Oscillator Force Field.
Kumar A, Pandey P, Chatterjee P, MacKerell AD, Kumar A, Pandey P, Chatterjee P, MacKerell AD. 2022. Deep Neural Network Model to Predict the Electrostatic Parameters in the Polarizable Classical Drude Oscillator Force Field. Journal of chemical theory and computation : . DOI: 10.1021/acs.jctc.1c01166
Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N).
Chao KL, Shang X, Greenfield J, Linden SB, Alreja AB, Nelson DC, Herzberg O, Chao KL, Shang X, Greenfield J, Linden SB, Alreja AB, Nelson DC, Herzberg O. 2022. Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N). Scientific reports 12(1): 2061. DOI: 10.1038/s41598-022-06073-2
An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking.
Dey D, Singh S, Khan S, Martin M, Schnicker NJ, Gakhar L, Pierce BG, Hasan SS, Dey D, Singh S, Khan S, Martin M, Schnicker NJ, Gakhar L, Pierce BG, Hasan SS. 2022. An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking. Communications biology 5(1): 115. DOI: 10.1038/s42003-022-03063-y
T cell receptors (TCRs) employ diverse strategies to target a p53 cancer neoantigen.
Wu D, Gowathaman R, Pierce BG, Mariuzza RA, Wu D, Gowathaman R, Pierce BG, Mariuzza RA. 2022. T cell receptors (TCRs) employ diverse strategies to target a p53 cancer neoantigen. The Journal of biological chemistry : 101684. DOI: 10.1016/j.jbc.2022.101684
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.
Beaudoin-Bussières G, Chen Y, Ullah I, Prévost J, Tolbert WD, Symmes K, Ding S, Benlarbi M, Gong SY, Tauzin A, et al. 2022. A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection. Cell reports : 110368. DOI: 10.1016/j.celrep.2022.110368
Electrogenetic Signal Transmission and Propagation in Coculture to Guide Production of a Small Molecule, Tyrosine.
VanArsdale E, Pitzer J, Wang S, Stephens K, Chen CY, Payne GF, Bentley WE, VanArsdale E, Pitzer J, Wang S, Stephens K, Chen CY, Payne GF, Bentley WE. 2022. Electrogenetic Signal Transmission and Propagation in Coculture to Guide Production of a Small Molecule, Tyrosine. ACS synthetic biology : . DOI: 10.1021/acssynbio.1c00522
Electro-assembly of a dynamically adaptive molten fibril state for collagen.
Lei M, Qu X, Wan H, Jin D, Wang S, Zhao Z, Yin M, Payne GF, Liu C, Lei M, Qu X, Wan H, Jin D, Wang S, Zhao Z, Yin M, Payne GF, Liu C. 2022. Electro-assembly of a dynamically adaptive molten fibril state for collagen. Science advances 8(5): eabl7506. DOI: 10.1126/sciadv.abl7506
Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Hiregange DG, Rivalta A, Bose T, Breiner-Goldstein E, Samiya S, Cimicata G, Kulakova L, Zimmerman E, Bashan A, Herzberg O, et al. 2022. Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. Nucleic acids research : . DOI: 10.1093/nar/gkac046
Computational and Experimental Characterization of rDNA and rRNA G-Quadruplexes.
Green AT, Pickard AJ, Li R, MacKerell AD, Bierbach U, Cho SS, Green AT, Pickard AJ, Li R, MacKerell AD, Bierbach U, Cho SS. 2022. Computational and Experimental Characterization of rDNA and rRNA G-Quadruplexes. The journal of physical chemistry. B : . DOI: 10.1021/acs.jpcb.1c08340
Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Wu D, Kolesnikov A, Yin R, Guest JD, Gowthaman R, Shmelev A, Serdyuk Y, Dianov DV, Efimov GA, Pierce BG, et al. 2022. Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nature communications 13(1): 19. DOI: 10.1038/s41467-021-27669-8
Cationic Fluoropolyphosphazenes: Synthesis and Assembly with Heparin as a Pathway to Hemocompatible Nanocoatings.
Marin A, Brito J, Sukhishvili SA, Andrianov AK, Marin A, Brito J, Sukhishvili SA, Andrianov AK. 2021. Cationic Fluoropolyphosphazenes: Synthesis and Assembly with Heparin as a Pathway to Hemocompatible Nanocoatings. ACS applied bio materials 5(1): 313–321. DOI: 10.1021/acsabm.1c01099
Circular Dichroism Spectral Similarity Plots to Extend Validation and Correction to All Measured Wavelengths.
Meuse CW, Meuse CW. 2022. Circular Dichroism Spectral Similarity Plots to Extend Validation and Correction to All Measured Wavelengths. Applied spectroscopy N/A: N/A. DOI: 10.1177/00037028211057129
Solution Structures of Bacillus anthracis Protective Antigen Proteins Using Small Angle Neutron Scattering and Protective Antigen 63 Ion Channel Formation Kinetics.
Michelman-Ribeiro A, Rubinson KA, Silin V, Kasianowicz JJ, Michelman-Ribeiro A, Rubinson KA, Silin V, Kasianowicz JJ. 2021. Solution Structures of <i>Bacillus anthracis</i> Protective Antigen Proteins Using Small Angle Neutron Scattering and Protective Antigen 63 Ion Channel Formation Kinetics. Toxins 13(12): . DOI: 10.3390/toxins13120888
Excipient Innovation Through Precompetitive Research.
Yu YB, Taraban MB, Briggs KT, Brinson RG, Marino JP, Yu YB, Taraban MB, Briggs KT, Brinson RG, Marino JP. 2021. Excipient Innovation Through Precompetitive Research. Pharmaceutical research 38(12): 2179-2184. DOI: 10.1007/s11095-021-03157-y
Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p.
Imperatore JA, Cunningham CL, Pellegrene KA, Brinson RG, Marino JP, Evanseck JD, Mihailescu MR, Imperatore JA, Cunningham CL, Pellegrene KA, Brinson RG, Marino JP, Evanseck JD, Mihailescu MR. 2021. Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p. Nucleic acids research : . DOI: 10.1093/nar/gkab1226
HDX-MS and MD Simulations Provide Evidence for Stabilization of the IgG1-FcγRIa (CD64a) Immune Complex Through Intermolecular Glycoprotein Bonds.
Anderson KW, Bergonzo C, Scott K, Karageorgos IL, Gallagher ES, Tayi VS, Butler M, Hudgens JW, Anderson KW, Bergonzo C, Scott K, Karageorgos IL, Gallagher ES, Tayi VS, Butler M, Hudgens JW. 2021. HDX-MS and MD Simulations Provide Evidence for Stabilization of the IgG1-FcγRIa (CD64a) Immune Complex Through Intermolecular Glycoprotein Bonds. Journal of molecular biology 434(2): 167391. DOI: 10.1016/j.jmb.2021.167391
Practical Applications of NMR to Solve Real-World Problems.
Brinson RG, Brinson RG. 2021. Practical Applications of NMR to Solve Real-World Problems. Molecules (Basel, Switzerland) 26(23): . DOI: 10.3390/molecules26237091
N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity.
Karade SS, Hill ML, Kiappes JL, Manne R, Aakula B, Zitzmann N, Warfield KL, Treston AM, Mariuzza RA, Karade SS, Hill ML, Kiappes JL, Manne R, Aakula B, Zitzmann N, Warfield KL, Treston AM, Mariuzza RA. 2021. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. Journal of medicinal chemistry 64(24): 18010-18024. DOI: 10.1021/acs.jmedchem.1c01377
Nano-Assembly of Quisinostat and Biodegradable Macromolecular Carrier Results in Supramolecular Complexes with Slow-Release Capabilities.
Chowdhury A, Marin A, Weber DJ, Andrianov AK, Chowdhury A, Marin A, Weber DJ, Andrianov AK. 2021. Nano-Assembly of Quisinostat and Biodegradable Macromolecular Carrier Results in Supramolecular Complexes with Slow-Release Capabilities. Pharmaceutics 13(11): . DOI: 10.3390/pharmaceutics13111834