IBBR Publications

Found 258 results
Filters: Keyword is Binding Sites  [Clear All Filters]
2007
Thompson LC, Ladner JE, Codreanu SG, Harp J, Gilliland GL, Armstrong RN. 2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida. Biochemistry. 2007 ;46(23):6710-22.
Zhong S, Mackerell AD. Binding response: a descriptor for selecting ligand binding site on protein surfaces. J Chem Inf Model. 2007 ;47(6):2303-15.
Galkin A, Kulakova L, Melamud E, Li L, Wu C, Mariano P, Dunaway-Mariano D, Nash TE, Herzberg O. Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia. J Biol Chem. 2007 ;282(7):4859-67.
Alexander PA, He Y, Chen Y, Orban J, Bryan PN. The design and characterization of two proteins with 88% sequence identity but different structure and function. Proc Natl Acad Sci U S A. 2007 ;104(29):11963-8.
Vögeli B, Ying J, Grishaev A, Bax A. Limits on variations in protein backbone dynamics from precise measurements of scalar couplings. J Am Chem Soc. 2007 ;129(30):9377-85.
Fisher KE, Ruan B, Alexander PA, Wang L, Bryan PN. Mechanism of the kinetically-controlled folding reaction of subtilisin. Biochemistry. 2007 ;46(3):640-51.
Bolisay LD, Culver JN, Kofinas P. Optimization of virus imprinting methods to improve selectivity and reduce nonspecific binding. Biomacromolecules. 2007 ;8(12):3893-9.
Parsons JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE. Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. Biochemistry. 2007 ;46(7):1821-8.
Cho S, Wang Q, Swaminathan CP, Hesek D, Lee M, Boons G-J, Mobashery S, Mariuzza RA. Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc Natl Acad Sci U S A. 2007 ;104(21):8761-6.
Chao KL, Muthukumar L, Herzberg O. Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis. Biochemistry. 2007 ;46(23):6911-20.
Lim K, Read RJ, Chen CCH, Tempczyk A, Wei M, Ye D, Wu C, Dunaway-Mariano D, Herzberg O. Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry. 2007 ;46(51):14845-53.
2006
Fernández MM, De Marzi MC, Berguer P, Burzyn D, Langley RJ, Piazzon I, Mariuzza RA, Malchiodi EL. Binding of natural variants of staphylococcal superantigens SEG and SEI to TCR and MHC class II molecule. Mol Immunol. 2006 ;43(7):927-38.
Chen F, Hancock CN, Macias AT, Joh J, Still K, Zhong S, Mackerell AD, Shapiro P. Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure. Bioorg Med Chem Lett. 2006 ;16(24):6281-7.
Walsh STR, Kossiakoff AA. Crystal structure and site 1 binding energetics of human placental lactogen. J Mol Biol. 2006 ;358(3):773-84.
Fernández MM, Guan R, Swaminathan CP, Malchiodi EL, Mariuzza RA. Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule. J Biol Chem. 2006 ;281(35):25356-64.
Natarajan K, Hicks A, Mans J, Robinson H, Guan R, Mariuzza RA, Margulies DH. Crystal structure of the murine cytomegalovirus MHC-I homolog m144. J Mol Biol. 2006 ;358(1):157-71.
Hancock CN, Macias AT, Mackerell AD, Shapiro P. Mitogen activated protein (MAP) kinases: development of ATP and non-ATP dependent inhibitors. Med Chem. 2006 ;2(2):213-22.
Chen CCH, Han Y, Niu W, Kulakova AN, Howard A, Quinn JP, Dunaway-Mariano D, Herzberg O. Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily. Biochemistry. 2006 ;45(38):11491-504.
Teplyakov A, Lim K, Zhu P-P, Kapadia G, Chen CCH, Schwartz J, Howard A, Reddy PT, Peterkofsky A, Herzberg O. Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein. Proc Natl Acad Sci U S A. 2006 ;103(44):16218-23.
D Gallagher T, Smith NN, Kim S-K, Heroux A, Robinson H, Reddy PT. Structure of the class IV adenylyl cyclase reveals a novel fold. J Mol Biol. 2006 ;362(1):114-22.