IBBR Publications

Found 258 results
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Lim K, Tempczyk A, Bonander N, Toedt J, Howard A, Eisenstein E, Herzberg O. A catalytic mechanism for D-Tyr-tRNATyr deacylase based on the crystal structure of Hemophilus influenzae HI0670. J Biol Chem. 2003 ;278(15):13496-502.
Svitel J, Balbo A, Mariuzza RA, Gonzales NR, Schuck P. Combined affinity and rate constant distributions of ligand populations from experimental surface binding kinetics and equilibria. Biophys J. 2003 ;84(6):4062-77.
Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, R Camerini-Otero D, Gilliland GL. Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site. BMC Struct Biol. 2003 ;3:7.
Toth EA, Li Y, Sawaya MR, Cheng Y, Ellenberger T. The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Mol Cell. 2003 ;12(5):1113-23.
Teplyakov A, Obmolova G, Chu SY, Toedt J, Eisenstein E, Howard AJ, Gilliland GL. Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid. J Bacteriol. 2003 ;185(14):4031-7.
Yang J, Swaminathan CP, Huang Y, Guan R, Cho S, Kieke MC, Kranz DM, Mariuzza RA, Sundberg EJ. Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface. J Biol Chem. 2003 ;278(50):50412-21.
Zavala-Ruiz Z, Sundberg EJ, Stone JD, DeOliveira DB, Chan IC, Svendsen J, Mariuzza RA, Stern LJ. Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1. J Biol Chem. 2003 ;278(45):44904-12.
Lehmann C, Lim K, Chalamasetty VRao, Krajewski W, Melamud E, Galkin A, Howard A, Kelman Z, Reddy PT, Murzin AG, et al. The HI0073/HI0074 protein pair from Haemophilus influenzae is a member of a new nucleotidyltransferase family: structure, sequence analyses, and solution studies. Proteins. 2003 ;50(2):249-60.
Wilder PT, Baldisseri DM, Udan R, Vallely KM, Weber DJ. Location of the Zn(2+)-binding site on S100B as determined by NMR spectroscopy and site-directed mutagenesis. Biochemistry. 2003 ;42(46):13410-21.
Zimmer DB, Sadosky PWright, Weber DJ. Molecular mechanisms of S100-target protein interactions. Microsc Res Tech. 2003 ;60(6):552-9.
DeJong ES, Chang C-en, Gilson MK, Marino JP. Proflavine acts as a Rev inhibitor by targeting the high-affinity Rev binding site of the Rev responsive element of HIV-1. Biochemistry. 2003 ;42(26):8035-46.
Huang N, Banavali NK, Mackerell AD. Protein-facilitated base flipping in DNA by cytosine-5-methyltransferase. Proc Natl Acad Sci U S A. 2003 ;100(1):68-73.
Walsh STR, Jevitts LM, Sylvester JE, Kossiakoff AA. Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization. Protein Sci. 2003 ;12(9):1960-70.
Parsons L, Bonander N, Eisenstein E, Gilson M, Kairys V, Orban J. Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family. Biochemistry. 2003 ;42(1):80-9.
Sundberg EJ, Andersen PS, Schlievert PM, Karjalainen K, Mariuzza RA. Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation. Structure. 2003 ;11(9):1151-61.
Lim K, Zhang H, Tempczyk A, Krajewski W, Bonander N, Toedt J, Howard A, Eisenstein E, Herzberg O. Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a cofactor bound at a site formed by a knot. Proteins. 2003 ;51(1):56-67.
Clement OO, Freeman CM, Hartmann RW, Handratta VD, Vasaitis TS, Brodie AMH, Njar VCO. Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy. J Med Chem. 2003 ;46(12):2345-51.
Wang Z, Moult J. Three-dimensional structural location and molecular functional effects of missense SNPs in the T cell receptor Vbeta domain. Proteins. 2003 ;53(3):748-57.
Li Y, Li H, Yang F, Smith-Gill SJ, Mariuzza RA. X-ray snapshots of the maturation of an antibody response to a protein antigen. Nat Struct Biol. 2003 ;10(6):482-8.