Publications

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Targeting of protein translation as a new treatment paradigm for prostate cancer.
Ramamurthy VP, Ramalingam S, Kwegyir-Afful AK, Hussain A, Njar VCO. 2017. Targeting of protein translation as a new treatment paradigm for prostate cancer. Current opinion in oncology 29(3): 210-220. DOI: 10.1097/CCO.0000000000000367
The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis.
Quigley J, Hughitt VK, Velikovsky CA, Mariuzza RA, El-Sayed NM, Briken V. 2017. The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of <i>Mycobacterium tuberculosis</i>. mBio 8(2): . DOI: 10.1128/mBio.00148-17
Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation.
Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, MacKerell AD, Jiang C, Xue F. 2017. Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation. The Journal of organic chemistry 82(7): 3589-3596. DOI: 10.1021/acs.joc.7b00106
Capillary Microfluidics-Assembled Virus-like Particle Bionanoreceptor Interfaces for Label-Free Biosensing.
Zang F, Gerasopoulos K, Brown AD, Culver JN, Ghodssi R. 2017. Capillary Microfluidics-Assembled Virus-like Particle Bionanoreceptor Interfaces for Label-Free Biosensing. ACS applied materials & interfaces 9(10): 8471-8479. DOI: 10.1021/acsami.6b14045
Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.
Mast N, Anderson KW, Lin JB, Li Y, Turko IV, Tatsuoka C, Bjorkhem I, Pikuleva IA. 2017. Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum. The Journal of biological chemistry 292(12): 4913-4924. DOI: 10.1074/jbc.M116.774760
A new approach to quantification of mAb aggregates using peptide affinity probes.
Cheung CS, Anderson KW, Patel PM, Cade KL, Phinney KW, Turko IV. 2017. A new approach to quantification of mAb aggregates using peptide affinity probes. Scientific reports 7: 42497. DOI: 10.1038/srep42497
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein.
Chao KL, Kulakova L, Herzberg O. 2017. Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proceedings of the National Academy of Sciences of the United States of America 114(7): E1128-E1137. DOI: 10.1073/pnas.1616783114
ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes.
Borrman T, Cimons J, Cosiano M, Purcaro M, Pierce BG, Baker BM, Weng Z. 2017. ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes. Proteins 85(5): 908-916. DOI: 10.1002/prot.25260
TumbleScore: Run and tumble analysis for low frame-rate motility videos.
Pottash AE, McKay R, Virgile CR, Ueda H, Bentley WE. 2017. TumbleScore: Run and tumble analysis for low frame-rate motility videos. BioTechniques 62(1): 31-36. DOI: 10.2144/000114493
DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase.
Li H, Endutkin AV, Bergonzo C, Fu L, Grollman A, Zharkov DO, Simmerling C. 2017. DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase. Journal of the American Chemical Society 139(7): 2682-2692. DOI: 10.1021/jacs.6b11433
Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling.
Tschirhart T, Kim E, McKay R, Ueda H, Wu HC, Pottash AE, Zargar A, Negrete A, Shiloach J, Payne GF, et al. 2017. Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling. Nature communications 8: 14030. DOI: 10.1038/ncomms14030
Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles.
Ragaliauskas T, Mickevicius M, Rakovska B, Penkauskas T, Vanderah DJ, Heinrich F, Valincius G. 2017. Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles. Biochimica et biophysica acta. Biomembranes 1859(5): 669-678. DOI: 10.1016/j.bbamem.2017.01.015
Electrochemical reverse engineering: A systems-level tool to probe the redox-based molecular communication of biology.
Li J, Liu Y, Kim E, March JC, Bentley WE, Payne GF. 2017. Electrochemical reverse engineering: A systems-level tool to probe the redox-based molecular communication of biology. Free radical biology & medicine 105: 110-131. DOI: 10.1016/j.freeradbiomed.2016.12.029