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Xiao Lab Awarded $2M NIH MIRA Award for Groundbreaking Plant Biology Research
The Institute for Bioscience and Biotechnology Research (IBBR) is proud to announce that Dr. Shunyuan Xiao, IBBR Fellow and Professor in the University of Maryland’s Department of Plant Sciences and Landscape Architecture, has received a five-year, $2 million Maximizing Investigators’ Research Award (MIRA, R35) from the National Institutes of Health...
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IBBR Postdoc Takes 3rd Place in Flash Talk Competition at UMD’s Postdoctoral Research Symposium
Dr. Patrick Keating, a postdoctoral researcher in Dr. Jaekyun Jeon’s laboratory, earned 3rd place in the Flash Talk Competition at the University of Maryland’s 2025 Postdoctoral Research Symposium! The symposium’s second annual event showcased the breadth of postdoctoral research across the University System of Maryland, providing a dynamic platform for...
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New Term ‘Translon’ Proposed to Standardize Genetic Technology
A recent publication in Nature Methods introduced a new term, ‘translon,’ to denote any region of genetic code that is translated. The article, entitled "Translon: a single term for translated regions,” was co-authored by an international team of researchers including Dr. Jonathan Dinman, Director of IBBR.
About IBBR
IBBR is a joint research enterprise of the University of Maryland, College Park, the University of Maryland, Baltimore, and the National Institute of Standards and Technology.
IBBR leverages state-of-art integrative methods for bioanalytical, biophysical and structural characterization of biomolecules: cryo-electron microscopy, nuclear magnetic resonance, x-ray crystallography, small angle neutron and x-ray scattering and mass spectrometry.
IBBR researchers seek to advance therapeutic development, biomanufacturing, and state-of-the-art measurement technologies, to support accelerated delivery of safe and effective medicines to the public.
IBBR is a major initiative and supported in part by the University of Maryland Strategic Partnership: MPowering the State (MPower) , an initiative designed to achieve innovation and impact through collaboration.
Connecting
IBBR Commons
Sophisticated state-of-the-art instrumentation and facilities, and in-house expertise located in shared space and dedicated to advance research, support collaboration and foster innovation of methods. Instrumentation and facilities include tools for high-resolution structural biology, bioanalytical and biophysical measurement, protein engineering and cell culture, advanced computation including artificial intelligence and deep learning methods, and general laboratory services. These capabilities and advanced training are available to IBBR scientists and collaborators.
IBBR Postdoc Program
The IBBR Postdoc Program (IPP) focuses on collaborative research involving basic science and technology development that advances therapeutic development, vaccine development, and biomanufacturing. IPP Fellow project teams are designed with a combination of the IPP Fellow career goals and priorities of project mentors who can be from academic, government, and/or industrial laboratories throughout the University of Maryland, NIST and the I-270 corridor.
NMRPipe
IBBR is home to NMRPipe, a popular collection of programs and scripts for manipulating multidimensional Nuclear Magnetic Resonance (NMR) data. The use of NMRPipe is noted in roughly 40% of all NMR structures accepted into the Protein Data Bank.
Upcoming Events
BMD Staff Seminar S. Hilburg/ Z. Goecker, .03/.04
Tuesday, December 16, 2025 - 11:00am
Wednesday, December 17, 2025 - 11:00am
BMD Staff Seminar R. Allsopp/ W. Vreeland, .03/.07
Tuesday, January 6, 2026 - 11:00am
Recent Publications
Structural insights into clonal restriction and diversity in T cell recognition of two immunodominant SARS-CoV-2 nucleocapsid epitopes.
T cells play a crucial role in clearing SARS-CoV-2 and in forming long-term memory responses to that coronavirus. The highly immunogenic nucleocapsid (N) protein of SARS-CoV-2 is much more...
Magnetodynamics of short nanoparticle chains.
In recent years, there has been increasing interest in the understanding and application of nanoparticle assemblies driven by external fields. Although these systems can exhibit marked transitions...
ICAM-1 Targeting of Nanocarriers in a Human Blood-Brain-Barrier-on-a-Chip Complements In Vivo Brain Delivery Observations.
Targeting therapeutic nanocarriers (NCs) to endothelial receptors favors transport across the blood-brain barrier (BBB), a main obstacle to access the brain. While these strategies compel...
Genetically-Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model.
Inflammatory bowel diseases (IBD) affect over 6 million people globally and current treatments achieve only 10-20% rates of durable disease remission. Bacterial extracellular vesicles (BEVs) from...
The conserved bridging domain on HCV E1E2 glycoprotein complex is targeted by neutralizing antibodies from diverse lineages.
The induction of potent and cross-reactive neutralizing antibody (nAb) responses remains a challenge in vaccine development against antigenically diverse viruses such as hepatitis C virus (HCV)....