IBBR's Insect Transformation Facility (ITF) promotes the advancement of insect molecular science and its application to human health and welfare. The ITF is an international resource for the creation of genetically modified insects, development of new modification technologies, and provides training in the use of insect modification technologies. It also provides a variety of services related to the creation of transformant insects including embryo microinjections, transformant strain production and characterization.
The ITF staff are skilled in creating transgenic insects such as flies of agricultural and biomedical importance including the mosquitoes Aedes aegypti, Anopheles stephensi, and Anopheles gambiae as well as transgenic Lepidoptera and Coleoptera. The facility has been designed to be flexible and adaptable to accommodate a wide variety of projects.
Researchers with particular insects of interest are encouraged to contact the Facility to discuss options that are available to deal with their unique needs.
The ITF has the capabilities and capacity to perform all steps required for transgenic insect strain production and characterization. Clients can use some or all of the Facility’s capabilities. For example, the Facility can perform insect embryo microinjections to create G0 insects that the clients then rear and screen in their own laboratory.
The facility also provides consulting and training allowing researchers to use the microinjection suite to perform their own micromanipulations.
- 2,500 sq. ft. of laboratory space
- Microinjection suite with anti-vibration tables to accomodate up to three teams of researchers
- Abundant insect rearing space adjacent to microscopy and laboratory spaces
- Animal facilities to house multiple species of small animals