|Drs. John Orban and Philip Bryan Together Designed and Developed a System that Examines Mutational Requirements for Transitioning Between Folds and Functions||
The laboratories of Drs. John Orban and Philip Bryan at the University of Maryland Institute of Bioscience and Biotechnology Research (IBBR) have worked together to design and develop a system that examines the mutational requirements for transitioning between folds and functions. The group published the findings in the February 8 issue of the Cell Press journal Structure, authored by He et al., titled “Mutational Tipping Points for Switching Protein Folds and Functions”.
|Muro Group Receives Funding for Developing Therapeutic Strategies for Neurodegenerative Conditions||
Dr. Silvia Muro, Assistant Professor at the University of Maryland Institute of Bioscience and Biotechnology Research (IBBR) and the Fischell Department of Bioengineering, has been awarded funding to explore several therapeutic approaches using specific drug delivery platforms that have been developed in her lab. Dr. Muro’s project funding is through a collaboration with the NIH Chemical Genomics Center (NCGC) and the contract is associated with the NIH program for Therapeutics for Rare and Neglected Diseases (http://nctt.nih.gov/trnd/).
|Maria Ansar Awarded HHMI Fellowship||
Maria Ansar, an undergraduate student at the University of Maryland, was awarded a Howard Hughes Undergraduate Research Fellowship (HHMI). Ms. Ansar, who is an honors student in the Department of Cell Biology and Molecular Genetics, is working on her honors thesis in the lab of Dr. Silvia Muro, Assistant Professor at the University of Maryland Institute of Bioscience and Biotechnology Research (IBBR) and the Fischell Department of Bioengineering. The fellowship awarded to Ms.
|Dr. James Culver Awarded NSF Funding to Study How Viruses Reprogram Phloem Specific Tissues||
Dr. James Culver, Professor at the University of Maryland Institute of Bioscience and Biotechnology Research (IBBR) and Department of Plant Sciences and Landscape Architecture, has recently been awarded funding from the National Science Foundation to study how viruses reprogram phloem specific tissues to mediate their long distance transport. In vascular plants, the capacity of a virus to cause disease is often linked to its ability to move throughout host tissues.
|IBBR Researchers Develop Procedure for Screening Microbes for Broad-Spectrum Antibiotics Resistance||
Research from the laboratories of Drs. Shuwei Li (UM IBBR/CHEM&BCHM) and Daniel Nelson (UM IBBR/VETMED) has led to the development of a quick and sensitive procedure for screening microbes that are resistant to certain broad-spectrum antibiotics.
|Graduate Student Daniel Serrano Recipient of Research Award||
Daniel Serrano, a graduate student in the Molecular and Cellular Biology Concentration Area of the Biological Sciences Graduate Program at the University of Maryland, has been selected to receive a research award sponsored by the Nanomedicine and Drug Delivery Symposium that was recently held at the University of Utah in Salt Lake City. Serrano is a PhD candidate in the laboratory of Dr. Silvia Muro (IBBR and Fischell Department of Bioengineering).
|Graduate Student Robert Berkey Poster Places Among Top 5 Winners||
Molecular and Cellular Biology (MOCB) graduate student Robert Berkey, from the laboratory of Dr. Shunyuan Xiao (IBBR and PLSA) has placed among the top 5 winners of the UM College of Agriculture and Natural Resources (AGNR) 2011 Open House Poster Competition. The poster entitled " Engineering Novel Plant Disease Resistance against Fungal Pathogens " was selected from a pool of high quality posters and the top five were awarded a prize of $100. The posters were presented at the AGNR 2011 Open House on October 1.
|O'Brochta Researchers Developed a Powerful Forward-Genetics Transposon Technology||
Researchers in the laboratory of Dr. David O’Brochta, at the University of Maryland Institute of Bioscience and Biotechnology Research (IBBR) and Department of Entomology (ENT), have developed a powerful forward-genetics transposon technology that can be used to determine gene functions from the phenotypes arising from transposon insertion mutations. The group published the findings, titled “piggyBac transposon remobilization and enhancer detection in Anopheles mosquitoes”, in the Sept 27 issue of PNAS.
|Dr. Mariuzza's Research Group Finding Selected by F1000||
Researchers in the laboratory of Dr. Roy Mariuzza, at the University of Maryland Institute of Bioscience and Biotechnology Research (IBBR) and Department of Cell Biology and Molecular Genetics (CBMG), have developed unique tools for probing the influence of the interaction of immune cell receptors CD4 and MHC class II on T-cell activation and development. The group published the findings, titled “Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4–HLA-DR1 complex”, in the September 10 issue of PNAS.
|Bringing Next-Generation Sequencing Technology to the UM Research Community||
The Institute for Bioscience and Biotechnology Research (IBBR) is expanding its core services to include high throughput sequencing, based on the recent purchase of an Illumina HiSeq 1000 instrument plus supporting equipment. The instrument is located in the IBBR DNA Sequencing Facility on the 5th floor of the Plant Sciences Building on the College Park campus, which has offered Sanger sequencing for many years. The purchase of this “Next-Gen” instrument, the first on the UM campus, was facilitated by Dr.