Publications

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Structural Insights into the Mechanism of Base Excision by MBD4.
Pidugu LS, Bright H, Lin WJ, Majumdar C, Van Ostrand RP, David SS, Pozharski E, Drohat AC. 2021. Structural Insights into the Mechanism of Base Excision by MBD4. Journal of molecular biology 433(15): 167097. DOI: 10.1016/j.jmb.2021.167097
The emerging landscape of single-molecule protein sequencing technologies.
Alfaro JA, Bohländer P, Dai M, Filius M, Howard CJ, van Kooten XF, Ohayon S, Pomorski A, Schmid S, Aksimentiev A, et al. 2021. The emerging landscape of single-molecule protein sequencing technologies. Nature methods 18(6): 604-617. DOI: 10.1038/s41592-021-01143-1
Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin.
King H, Ajay Castro S, Pohane AA, Scholte CM, Fischetti VA, Korotkova N, Nelson DC, Dorfmueller HC. 2021. Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin. The Biochemical journal 478(12): 2385-2397. DOI: 10.1042/BCJ20210158
Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development.
Toth EA, Chagas A, Pierce BG, Fuerst TR. 2021. Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development. Viruses 13(6): . DOI: 10.3390/v13061027
Immunopotentiating and Delivery Systems for HCV Vaccines.
Andrianov AK, Fuerst TR. 2021. Immunopotentiating and Delivery Systems for HCV Vaccines. Viruses 13(6): . DOI: 10.3390/v13060981
Structure-Based and Rational Design of a Hepatitis C Virus Vaccine.
Guest JD, Pierce BG. 2021. Structure-Based and Rational Design of a Hepatitis C Virus Vaccine. Viruses 13(5): . DOI: 10.3390/v13050837
Structurally disordered C-terminal residues of GTP cyclohydrolase II are essential for its enzymatic activity.
Yadav S, Shinde RN, Singh S, Karthikeyan S, Singh B. 2022. Structurally disordered C-terminal residues of GTP cyclohydrolase II are essential for its enzymatic activity. Journal of biomolecular structure & dynamics 40(19): 9318-9331. DOI: 10.1080/07391102.2021.1926326
A method to improve quantitative radiotracing-based analysis of the in vivo biodistribution of drug carriers.
Roki N, Solomon M, Casta L, Bowers J, Getts RC, Muro S. 2021. A method to improve quantitative radiotracing-based analysis of the in vivo biodistribution of drug carriers. Bioengineering & translational medicine 6(2): e10208. DOI: 10.1002/btm2.10208
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, et al. 2021. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. bioRxiv : the preprint server for biology : . DOI: 10.1101/2021.05.10.443524
A simple approach for reconstruction of non-uniformly sampled pseudo-3D NMR data for accurate measurement of spin relaxation parameters.
East KW, Delaglio F, Lisi GP. 2021. A simple approach for reconstruction of non-uniformly sampled pseudo-3D NMR data for accurate measurement of spin relaxation parameters. Journal of biomolecular NMR 75(6-7): 213-219. DOI: 10.1007/s10858-021-00369-7
Reprogramming Virus Coat Protein Carboxylate Interactions for the Patterned Assembly of Hierarchical Nanorods.
Brown AD, Chu S, Kappagantu M, Ghodssi R, Culver JN. 2021. Reprogramming Virus Coat Protein Carboxylate Interactions for the Patterned Assembly of Hierarchical Nanorods. Biomacromolecules 22(6): 2515-2523. DOI: 10.1021/acs.biomac.1c00258
Supramolecular assembly of Toll-like receptor 7/8 agonist into multimeric water-soluble constructs enables superior immune stimulation in vitro and in vivo.
Andrianov AK, Marin A, Wang R, Karauzum H, Chowdhury A, Agnihotri P, Yunus AS, Mariuzza RA, Fuerst TR. 2020. Supramolecular assembly of Toll-like receptor 7/8 agonist into multimeric water-soluble constructs enables superior immune stimulation <i>in vitro</i> and <i>in vivo</i>. ACS applied bio materials 3(5): 3187-3195. DOI: 10.1021/acsabm.0c00189
Protective antibodies against human parainfluenza virus type 3 infection.
Boonyaratanakornkit J, Singh S, Weidle C, Rodarte J, Bakthavatsalam R, Perkins J, Stewart-Jones GBE, Kwong PD, McGuire AT, Pancera M, et al. 2021. Protective antibodies against human parainfluenza virus type 3 infection. mAbs 13(1): 1912884. DOI: 10.1080/19420862.2021.1912884
Single-Step Synthesis of Alginate Microgels Enveloped with a Covalent Polymeric Shell: A Simple Way to Protect Encapsulated Cells.
Ahn SH, Rath M, Tsao CY, Bentley WE, Raghavan SR. 2021. Single-Step Synthesis of Alginate Microgels Enveloped with a Covalent Polymeric Shell: A Simple Way to Protect Encapsulated Cells. ACS applied materials & interfaces 13(16): 18432-18442. DOI: 10.1021/acsami.0c20613
Bacterial Extracellular Vesicles and the Gut-Microbiota Brain Axis: Emerging Roles in Communication and Potential as Therapeutics.
Pirolli NH, Bentley WE, Jay SM. 2021. Bacterial Extracellular Vesicles and the Gut-Microbiota Brain Axis: Emerging Roles in Communication and Potential as Therapeutics. Advanced biology 5(7): e2000540. DOI: 10.1002/adbi.202000540