Publications

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Comparative modeling in structural genomics.
Moult J, Moult J. 2008. Comparative modeling in structural genomics. Structure (London, England : 1993) 16(1): 14-6. DOI: 10.1016/j.str.2007.12.001
RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1.
Garnacho C, Shuvaev V, Thomas A, McKenna L, Sun J, Koval M, Albelda S, Muzykantov V, Muro S, Garnacho C, Shuvaev V, Thomas A, McKenna L, Sun J, Koval M, Albelda S, Muzykantov V, Muro S. 2008. RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. Blood 111(6): 3024-33. DOI: 10.1182/blood-2007-06-098657
Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts.
Gediya LK, Belosay A, Khandelwal A, Purushottamachar P, Njar VC, Gediya LK, Belosay A, Khandelwal A, Purushottamachar P, Njar VC. 2008. Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. Bioorganic & medicinal chemistry 16(6): 3352-60. DOI: 10.1016/j.bmc.2007.12.007
Inhibition of protein-protein interactions with low molecular weight compounds.
Matthews MM, Weber DJ, Shapiro PS, Coop A, Mackerell AD, Matthews MM, Weber DJ, Shapiro PS, Coop A, Mackerell AD. 2008. Inhibition of protein-protein interactions with low molecular weight compounds. Current trends in medicinal chemistry 5: 21-32.
The Design and Synthesis of Highly Branched and Spherically Symmetric Fluorinated Macrocyclic Chelators.
Jiang ZX, Yu YB, Jiang ZX, Yu YB. 2008. The Design and Synthesis of Highly Branched and Spherically Symmetric Fluorinated Macrocyclic Chelators. Synthesis 2008(2): 215-220.
Self-assembly of virus-structured high surface area nanomaterials and their application as battery electrodes.
Royston E, Ghosh A, Kofinas P, Harris MT, Culver JN, Royston E, Ghosh A, Kofinas P, Harris MT, Culver JN. 2008. Self-assembly of virus-structured high surface area nanomaterials and their application as battery electrodes. Langmuir : the ACS journal of surfaces and colloids 24(3): 906-12.
Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome.
Bernstein J, Patterson DN, Wilson GM, Toth EA, Bernstein J, Patterson DN, Wilson GM, Toth EA. 2008. Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome. The Journal of biological chemistry 283(8): 4930-42.
Tobacco mosaic virus replicase-auxin/indole acetic acid protein interactions: reprogramming the auxin response pathway to enhance virus infection.
Padmanabhan MS, Kramer SR, Wang X, Culver JN, Padmanabhan MS, Kramer SR, Wang X, Culver JN. 2008. Tobacco mosaic virus replicase-auxin/indole acetic acid protein interactions: reprogramming the auxin response pathway to enhance virus infection. Journal of virology 82(5): 2477-85.
S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling.
Prosser BL, Wright NT, Hernãndez-Ochoa EO, Varney KM, Liu Y, Olojo RO, Zimmer DB, Weber DJ, Schneider MF, Prosser BL, Wright NT, Hernãndez-Ochoa EO, Varney KM, Liu Y, Olojo RO, Zimmer DB, Weber DJ, Schneider MF. 2008. S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling. The Journal of biological chemistry 283(8): 5046-57.
Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily.
Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O, Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O. 2008. Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily. Biochemistry 47(1): 167-82.
In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium.
Rossin R, Muro S, Welch MJ, Muzykantov VR, Schuster DP, Rossin R, Muro S, Welch MJ, Muzykantov VR, Schuster DP. 2008. In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 49(1): 103-11.
A new nitrilase from Bradyrhizobium japonicum USDA 110. Gene cloning, biochemical characterization and substrate specificity.
Zhu D, Mukherjee C, Yang Y, Rios BE, Gallagher DT, Smith NN, Biehl ER, Hua L, Zhu D, Mukherjee C, Yang Y, Rios BE, Gallagher DT, Smith NN, Biehl ER, Hua L. 2008. A new nitrilase from Bradyrhizobium japonicum USDA 110. Gene cloning, biochemical characterization and substrate specificity. Journal of biotechnology 133(3): 327-33.
Swiveling domain mechanism in pyruvate phosphate dikinase.
Lim K, Read RJ, Chen CC, Tempczyk A, Wei M, Ye D, Wu C, Dunaway-Mariano D, Herzberg O, Lim K, Read RJ, Chen CC, Tempczyk A, Wei M, Ye D, Wu C, Dunaway-Mariano D, Herzberg O. 2007. Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry 46(51): 14845-53.
Main chain NMR assignments of subtilisin Sbt70 in its prodomain-bound state.
Sari N, Fisher KE, Bryan PN, Orban J, Sari N, Fisher KE, Bryan PN, Orban J. 2007. Main chain NMR assignments of subtilisin Sbt70 in its prodomain-bound state. Biomolecular NMR assignments 1(2): 209-11. DOI: 10.1007/s12104-007-9058-4
Toxicogenomic response to chlorination includes induction of major virulence genes in Staphylococcus aureus.
Chang MW, Toghrol F, Bentley WE, Chang MW, Toghrol F, Bentley WE. 2007. Toxicogenomic response to chlorination includes induction of major virulence genes in Staphylococcus aureus. Environmental science & technology 41(21): 7570-5.