Publications

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A new simple and high-yield synthesis of 5α-dihydrotestosterone (DHT), a potent androgen receptor agonist.
Purushottamachar P, Njar VC. 2012. A new simple and high-yield synthesis of 5α-dihydrotestosterone (DHT), a potent androgen receptor agonist. Steroids 77(14): 1530-4. DOI: 10.1016/j.steroids.2012.09.003
The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.
Tran K, Risingsong R, Royce DB, Williams CR, Sporn MB, Pioli PA, Gediya LK, Njar VC, Liby KT. 2013. The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer. Carcinogenesis 34(1): 199-210. DOI: 10.1093/carcin/bgs319
Avoiding steric congestion in dendrimer growth through proportionate branching: a twist on da Vinci's rule of tree branching.
Yue X, Taraban MB, Hyland LL, Yu YB. 2012. Avoiding steric congestion in dendrimer growth through proportionate branching: a twist on da Vinci's rule of tree branching. The Journal of organic chemistry 77(20): 8879-87. DOI: 10.1021/jo301718y
Population diversity of ORFan genes in Escherichia coli.
Yu G, Stoltzfus A. 2012. Population diversity of ORFan genes in Escherichia coli. Genome biology and evolution 4(11): 1176-87. DOI: 10.1093/gbe/evs081
Sugar-binding proteins from fish: selection of high affinity "lambodies" that recognize biomedically relevant glycans.
Hong X, Ma MZ, Gildersleeve JC, Chowdhury S, Barchi JJ, Mariuzza RA, Murphy MB, Mao L, Pancer Z. 2013. Sugar-binding proteins from fish: selection of high affinity "lambodies" that recognize biomedically relevant glycans. ACS chemical biology 8(1): 152-60. DOI: 10.1021/cb300399s
Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics.
Zhu J, O'Dell S, Ofek G, Pancera M, Wu X, Zhang B, Zhang Z, , Mullikin JC, Simek M, et al. 2012. Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics. Frontiers in microbiology 3: 315.
Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum.
He Y, Chen Y, Oganesyan N, Ruan B, O'Brochta D, Bryan PN, Orban J. 2012. Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins 80(12): 2810-7. DOI: 10.1002/prot.24187
Novel structural features of xylanase A1 from Paenibacillus sp. JDR-2.
St John FJ, Preston JF, Pozharski E. 2012. Novel structural features of xylanase A1 from Paenibacillus sp. JDR-2. Journal of structural biology 180(2): 303-11. DOI: 10.1016/j.jsb.2012.09.007
Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.
Zhang MY, Yuan T, Li J, Rosa Borges A, Watkins JD, Guenaga J, Yang Z, Wang Y, Wilson R, Li Y, et al. 2012. Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41. PloS one 7(9): e44241. DOI: 10.1371/journal.pone.0044241
Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor.
Papademetriou J, Garnacho C, Serrano D, Bhowmick T, Schuchman EH, Muro S. 2013. Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor. Journal of inherited metabolic disease 36(3): 467-77. DOI: 10.1007/s10545-012-9534-6
Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1.
Han J, Zern BJ, Shuvaev VV, Davies PF, Muro S, Muzykantov V. 2012. Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1. ACS nano 6(10): 8824-36. DOI: 10.1021/nn302687n
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors.
Wang J, Zhuang J, Iyer S, Lin X, Whitfield TW, Greven MC, Pierce BG, Dong X, Kundaje A, Cheng Y, et al. 2012. Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome research 22(9): 1798-812. DOI: 10.1101/gr.139105.112
On the variability of experimental data in macromolecular crystallography.
Pozharski E. 2012. On the variability of experimental data in macromolecular crystallography. Acta crystallographica. Section D, Biological crystallography 68(Pt 9): 1077-87. DOI: 10.1107/S0907444912020100
DNA binding specificity of ATAF2, a NAC domain transcription factor targeted for degradation by Tobacco mosaic virus.
Wang X, Culver JN. 2012. DNA binding specificity of ATAF2, a NAC domain transcription factor targeted for degradation by Tobacco mosaic virus. BMC plant biology 12: 157. DOI: 10.1186/1471-2229-12-157
ABRF-MIRG benchmark study: molecular interactions in a three-component system.
Yamniuk AP, Edavettal SC, Bergqvist S, Yadav SP, Doyle ML, Calabrese K, Parsons JF, Eisenstein E. 2012. ABRF-MIRG benchmark study: molecular interactions in a three-component system. Journal of biomolecular techniques : JBT 23(3): 101-14. DOI: 10.7171/jbt.12-2303-003